FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921405100> ?p ?o ?g. }

• W2921405100 endingPage "101769" @default.
• W2921405100 startingPage "101769" @default.
• W2921405100 abstract "Amyloid positivity is a biomarker of AD pathology, yet the associations between amyloid positivity and brain volumetric changes, especially in the hippocampus, are inconsistent. We hypothesize that sex differences in associations may contribute to inconsistent findings among cognitively normal older adults. Using linear mixed effects models, we examined the association of amyloid positivity with prospective volumetric changes (mean = 3.3 visits) of parahippocampal gyrus (phg), hippocampus, entorhinal cortex (erc), precuneus, and fusiform gyrus among 171 Baltimore Longitudinal Study of Aging participants aged ≥55 years. Amyloid positivity was defined by a mean 11C-Pittsburgh Compound B (PiB) distribution volume ratio (DVR) cut-off of 1.062. All analyses included age, race, sex, education, APOE e4 carrier status, and two-way interactions of these covariates with time. Two-way interaction between sex and PiB+/− status and three-way interaction of sex and PiB+/− status with time were added to assess whether sex modified associations. PiB+ status was associated with greater volumetric declines in the phg (β = −0.036, SE = 0.011, p = 0.001) and erc (β = −0.019, SE = 0.009, p = 0.045). Sex modified the association of PiB+ status and rates of volumetric declines in fusiform (β = −0.117, SE = 0.049, p = 0.019). PiB+ males had steeper rates of volumetric declines in phg (β = −0.051, SE = 0.013, p < 0.001) and erc (β = −0.029, SE = 0.012, p = 0.014) than PiB- males, while there was no difference in rates of volumetric change between PiB+ and PiB- females. Amyloidosis is a marker of entorhinal and parahippocampal volume loss. Amyloid positivity is a predictor of volume loss in brain regions affected by early AD pathology in men, but not women." @default.
• W2921405100 created "2019-03-22" @default.
• W2921405100 creator A5000122559 @default.
• W2921405100 creator A5003112344 @default.
• W2921405100 creator A5014732049 @default.
• W2921405100 creator A5029649151 @default.
• W2921405100 creator A5034999945 @default.
• W2921405100 creator A5045807277 @default.
• W2921405100 creator A5048196698 @default.
• W2921405100 creator A5072862654 @default.
• W2921405100 creator A5088495720 @default.
• W2921405100 creator A5089482025 @default.
• W2921405100 creator A5090023100 @default.
• W2921405100 date "2019-01-01" @default.
• W2921405100 modified "2023-09-27" @default.
• W2921405100 title "Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults" @default.
• W2921405100 cites W1929729372 @default.
• W2921405100 cites W1955491145 @default.
• W2921405100 cites W1966378897 @default.
• W2921405100 cites W1976076281 @default.
• W2921405100 cites W1980529166 @default.
• W2921405100 cites W1983821773 @default.
• W2921405100 cites W1992922736 @default.
• W2921405100 cites W1993571512 @default.
• W2921405100 cites W1998371341 @default.
• W2921405100 cites W1998633319 @default.
• W2921405100 cites W2021720039 @default.
• W2921405100 cites W2028436804 @default.
• W2921405100 cites W2030120613 @default.
• W2921405100 cites W2041694959 @default.
• W2921405100 cites W2044367669 @default.
• W2921405100 cites W2056123459 @default.
• W2921405100 cites W2074427084 @default.
• W2921405100 cites W2082939309 @default.
• W2921405100 cites W2090220821 @default.
• W2921405100 cites W2101241299 @default.
• W2921405100 cites W2101991516 @default.
• W2921405100 cites W2103861278 @default.
• W2921405100 cites W2108150542 @default.
• W2921405100 cites W2110424796 @default.
• W2921405100 cites W2111940573 @default.
• W2921405100 cites W2125960394 @default.
• W2921405100 cites W2131286474 @default.
• W2921405100 cites W2133719476 @default.
• W2921405100 cites W2134711807 @default.
• W2921405100 cites W2137454840 @default.
• W2921405100 cites W2148046162 @default.
• W2921405100 cites W2150481150 @default.
• W2921405100 cites W2152859618 @default.
• W2921405100 cites W2156220037 @default.
• W2921405100 cites W2159285109 @default.
• W2921405100 cites W2167720733 @default.
• W2921405100 cites W2171682279 @default.
• W2921405100 cites W2174862691 @default.
• W2921405100 cites W2196038229 @default.
• W2921405100 cites W2217874059 @default.
• W2921405100 cites W2257914755 @default.
• W2921405100 cites W2270987730 @default.
• W2921405100 cites W2509316616 @default.
• W2921405100 cites W2765468958 @default.
• W2921405100 cites W2803902280 @default.
• W2921405100 cites W2808227793 @default.
• W2921405100 cites W2808330206 @default.
• W2921405100 cites W2899253786 @default.
• W2921405100 cites W4211028926 @default.
• W2921405100 doi "https://doi.org/10.1016/j.nicl.2019.101769" @default.
• W2921405100 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6444285" @default.
• W2921405100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30927602" @default.
• W2921405100 hasPublicationYear "2019" @default.
• W2921405100 type Work @default.
• W2921405100 sameAs 2921405100 @default.
• W2921405100 citedByCount "19" @default.
• W2921405100 countsByYear W29214051002019 @default.
• W2921405100 countsByYear W29214051002020 @default.
• W2921405100 countsByYear W29214051002021 @default.
• W2921405100 countsByYear W29214051002022 @default.
• W2921405100 countsByYear W29214051002023 @default.
• W2921405100 crossrefType "journal-article" @default.
• W2921405100 hasAuthorship W2921405100A5000122559 @default.
• W2921405100 hasAuthorship W2921405100A5003112344 @default.
• W2921405100 hasAuthorship W2921405100A5014732049 @default.
• W2921405100 hasAuthorship W2921405100A5029649151 @default.
• W2921405100 hasAuthorship W2921405100A5034999945 @default.
• W2921405100 hasAuthorship W2921405100A5045807277 @default.
• W2921405100 hasAuthorship W2921405100A5048196698 @default.
• W2921405100 hasAuthorship W2921405100A5072862654 @default.
• W2921405100 hasAuthorship W2921405100A5088495720 @default.
• W2921405100 hasAuthorship W2921405100A5089482025 @default.
• W2921405100 hasAuthorship W2921405100A5090023100 @default.
• W2921405100 hasBestOaLocation W29214051001 @default.
• W2921405100 hasConcept C126322002 @default.
• W2921405100 hasConcept C142724271 @default.
• W2921405100 hasConcept C143998085 @default.
• W2921405100 hasConcept C15744967 @default.
• W2921405100 hasConcept C169760540 @default.
• W2921405100 hasConcept C169900460 @default.
• W2921405100 hasConcept C2777633098 @default.
• W2921405100 hasConcept C2777655717 @default.

• next