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- W2921446835 abstract "Introduction: Upper GI bleeding (UGIB) is associated with increased morbidity and mortality and places an increased cost burden on patients and hospitals. Recently several technological advancements, improvements in critical care and endoscopic procedures have focused on improving outcomes in this subset of patients. Our aim was to analyze the changes in mortality and length of stay in patients with variceal and non-variceal UGIB in the last 15 years. Methods: We analyzed > 300,000 records from a publicly available database (National Inpatient Sample) for UGIB outcomes and length of stay in patients from 2000 - 2014. Patients were categorized as variceal and non- variceal UGIB and analysis were adjusted for age, gender and presence of cirrhosis. Results: Overall age-adjusted mortality in UGIB decreased from 9.8% in 2000 to 6.7% in 2014 [p < 0.001]. However,overall length of stay remained unchanged from 6.8 days in 2000 to 6.4 days in 2014 [p=0.22]. Mortality in Variceal UGIB decreased from 9.2% to 6.3% [p<0.001]. Mortality in NV-GIB decreased from 12.4% in 2000 to 8.4 % in 2014 [p<0.001]. Mortality from Non variceal UGIB in patients was significantly higher than mortality from variceal UGIB [p<0.001] although the mortality owntrended for both subgroups in the last 15 years. Among patients UGIB, those with cirrhosis were more likely to die than those with other liver diseases. (OR=5.38; 95%CI: 4.87-5.94), after controlling for age, gender, and trend in years. Similarly patients with UGIB with cirrhosis had a 2.51-day higher LOS than patients with chronic liver disease. Conclusion: Mortality risk of UGIB has decreased considerably in the last 15 years. Through this entire time the length of hospital stay remained unchanged. NV-GIB is associated with increased mortality risk in patients, especially in patients with cirrhosis. There has been no direct study comparing mortality UGIB in patients with liver cirrhosis against other chronic liver disease but our study remains consistent with previous data that liver cirrhosis is an important determinant of increased morbidity and mortality in patients with UGIB." @default.
- W2921446835 created "2019-03-22" @default.
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- W2921446835 date "2018-10-01" @default.
- W2921446835 modified "2023-09-25" @default.
- W2921446835 title "Trend in Mortality in Variceal and Non-Variceal Gastrointestinal Bleeds Over 15 Years: A National Level Study: Presidential Poster Award" @default.
- W2921446835 doi "https://doi.org/10.14309/00000434-201810001-00555" @default.
- W2921446835 hasPublicationYear "2018" @default.
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