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- W2921548037 abstract "Intracerebral hemorrhage and ischemic stroke are increasingly recognized complications of central nervous system (CNS) infection by herpes simplex virus (HSV). To analyze clinical, imaging, and laboratory findings and outcomes of cerebrovascular manifestations of HSV infection. Systematic literature review from January 2000 to July 2018. We identified 38 patients (median age 45 years, range 1–73) comprising 27 cases of intracerebral hemorrhage, 10 of ischemic stroke, and 1 with cerebral venous sinus thrombosis. Intracerebral hemorrhage was predominantly (89%) a complication of HSV encephalitis located in the temporal lobe. Hematoma was present on the first brain imaging in 32%, and hematoma evacuation was performed in 30% of these cases. Infarction was frequently multifocal, and at times preceded by hemorrhage (20%). Both a stroke-like presentation and presence of HSV encephalitis in a typical location were rare (25% and 10%, respectively). There was evidence of cerebral vasculitis in 63%, which was exclusively located in large-sized vessels. Overall mortality was 21% for hemorrhage and 0% for infarction. HSV-1 was a major cause of hemorrhagic complications, whereas HSV-2 was the most prevalent agent in the ischemic manifestations. We found a distinct pathogenesis, cause, and outcome for HSV-related cerebral hemorrhage and infarction. Vessel disruption within a temporal lobe lesion caused by HSV-1 is the presumed mechanism for hemorrhage, which may potentially have a fatal outcome. Brain ischemia is mostly related to multifocal cerebral large vessel vasculitis associated with HSV-2, where the outcome is more favorable." @default.
- W2921548037 created "2019-03-22" @default.
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- W2921548037 date "2019-01-29" @default.
- W2921548037 modified "2023-10-17" @default.
- W2921548037 title "Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review" @default.
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- W2921548037 cites W1967041698 @default.
- W2921548037 cites W1975572510 @default.
- W2921548037 cites W1976322517 @default.
- W2921548037 cites W1981264926 @default.
- W2921548037 cites W1981978112 @default.
- W2921548037 cites W1986381982 @default.
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- W2921548037 cites W2016353167 @default.
- W2921548037 cites W2018409191 @default.
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- W2921548037 cites W2022119232 @default.
- W2921548037 cites W2023605992 @default.
- W2921548037 cites W2028346714 @default.
- W2921548037 cites W2028792108 @default.
- W2921548037 cites W2035684554 @default.
- W2921548037 cites W2035712499 @default.
- W2921548037 cites W2036984029 @default.
- W2921548037 cites W2050022388 @default.
- W2921548037 cites W2050114111 @default.
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- W2921548037 cites W2063703513 @default.
- W2921548037 cites W2074666408 @default.
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- W2921548037 cites W2083395837 @default.
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- W2921548037 cites W2092025461 @default.
- W2921548037 cites W2096669922 @default.
- W2921548037 cites W2101899401 @default.
- W2921548037 cites W2104403605 @default.
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- W2921548037 cites W2119296893 @default.
- W2921548037 cites W2132320401 @default.
- W2921548037 cites W2142703656 @default.
- W2921548037 cites W2148088096 @default.
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- W2921548037 cites W2255638973 @default.
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- W2921548037 cites W2328704029 @default.
- W2921548037 cites W2340501239 @default.
- W2921548037 cites W2404349720 @default.
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- W2921548037 cites W2576031176 @default.
- W2921548037 cites W2594466126 @default.
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- W2921548037 doi "https://doi.org/10.1186/s12974-019-1409-4" @default.
- W2921548037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6352343" @default.
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- W2921548037 hasPublicationYear "2019" @default.
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