FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921668693> ?p ?o ?g. }

• W2921668693 endingPage "344" @default.
• W2921668693 startingPage "344" @default.
• W2921668693 abstract "Background: Pathologic changes in cortical gray matter (GM) and leptomeninges contribute to disability worsening in patients with multiple sclerosis (MS), but there is little evidence whether disease-modifying treatments can slow down cortical pathology in MS. Objectives: To investigate the effect of teriflunomide (TFM) and dimethyl fumarate (DMF) in reducing cortical pathology, as determined by percentage cortical volume change (PCVC) and leptomeningeal contrast enhancement (LMCE) on MRI. Methods: This was a retrospective, single-center, observational study that selected 60 TFM- and 60 DMF-treated MS patients over 24 months. Results: TFM had a lower rate of PCVC compared to DMF over 24 months (−0.2% vs. −2.94%, p = 0.004). Similar results were observed for percentage GM volume change over 0–12 (p = 0.044) and 0–24 (−0.44% vs. −3.12%, p = 0.015) months. No significant differences were found between the TFM and DMF groups in the frequency and number of LMCE foci over the follow-up. TFM showed a numerically lower rate of whole brain atrophy over 24 months (p = 0.077), compared to DMF. No significant clinical or MRI lesion differences between TFM and DMF were detected over follow-up. Conclusions: These findings suggest that TFM has a superior effect on the preservation of cortical GM volume, compared to DMF." @default.
• W2921668693 created "2019-03-22" @default.
• W2921668693 creator A5005341542 @default.
• W2921668693 creator A5041234325 @default.
• W2921668693 creator A5055648634 @default.
• W2921668693 creator A5056204835 @default.
• W2921668693 creator A5062814951 @default.
• W2921668693 creator A5072623319 @default.
• W2921668693 creator A5075596287 @default.
• W2921668693 creator A5079130521 @default.
• W2921668693 creator A5080347094 @default.
• W2921668693 creator A5085028391 @default.
• W2921668693 date "2019-03-12" @default.
• W2921668693 modified "2023-10-17" @default.
• W2921668693 title "Effect of Teriflunomide and Dimethyl Fumarate on Cortical Atrophy and Leptomeningeal Inflammation in Multiple Sclerosis: A Retrospective, Observational, Case-Control Pilot Study" @default.
• W2921668693 cites W1585868767 @default.
• W2921668693 cites W1967838438 @default.
• W2921668693 cites W1988037885 @default.
• W2921668693 cites W1994083593 @default.
• W2921668693 cites W2009479470 @default.
• W2921668693 cites W2028942474 @default.
• W2921668693 cites W2043591841 @default.
• W2921668693 cites W2047062145 @default.
• W2921668693 cites W2048466191 @default.
• W2921668693 cites W2055250060 @default.
• W2921668693 cites W2065296899 @default.
• W2921668693 cites W2070525196 @default.
• W2921668693 cites W2078649420 @default.
• W2921668693 cites W2089940272 @default.
• W2921668693 cites W2093009907 @default.
• W2921668693 cites W2096479500 @default.
• W2921668693 cites W2100306095 @default.
• W2921668693 cites W2101539564 @default.
• W2921668693 cites W2102167158 @default.
• W2921668693 cites W2115041207 @default.
• W2921668693 cites W2118818657 @default.
• W2921668693 cites W2122545833 @default.
• W2921668693 cites W2125097811 @default.
• W2921668693 cites W2133329597 @default.
• W2921668693 cites W2142577589 @default.
• W2921668693 cites W2157401887 @default.
• W2921668693 cites W2164167069 @default.
• W2921668693 cites W2169159041 @default.
• W2921668693 cites W2274873287 @default.
• W2921668693 cites W2288914316 @default.
• W2921668693 cites W2337612449 @default.
• W2921668693 cites W2510681211 @default.
• W2921668693 cites W2548632358 @default.
• W2921668693 cites W2571231364 @default.
• W2921668693 cites W2610703760 @default.
• W2921668693 cites W2619002073 @default.
• W2921668693 cites W2742705326 @default.
• W2921668693 cites W2744408289 @default.
• W2921668693 cites W2766217184 @default.
• W2921668693 cites W2767362256 @default.
• W2921668693 cites W2781313989 @default.
• W2921668693 cites W2786777487 @default.
• W2921668693 cites W2791313094 @default.
• W2921668693 cites W2791439687 @default.
• W2921668693 cites W2890234116 @default.
• W2921668693 cites W2891800671 @default.
• W2921668693 cites W2896031745 @default.
• W2921668693 cites W2896879460 @default.
• W2921668693 cites W2903302543 @default.
• W2921668693 cites W2910356129 @default.
• W2921668693 cites W2912151872 @default.
• W2921668693 doi "https://doi.org/10.3390/jcm8030344" @default.
• W2921668693 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6463015" @default.
• W2921668693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30870983" @default.
• W2921668693 hasPublicationYear "2019" @default.
• W2921668693 type Work @default.
• W2921668693 sameAs 2921668693 @default.
• W2921668693 citedByCount "13" @default.
• W2921668693 countsByYear W29216686932019 @default.
• W2921668693 countsByYear W29216686932020 @default.
• W2921668693 countsByYear W29216686932021 @default.
• W2921668693 countsByYear W29216686932022 @default.
• W2921668693 countsByYear W29216686932023 @default.
• W2921668693 crossrefType "journal-article" @default.
• W2921668693 hasAuthorship W2921668693A5005341542 @default.
• W2921668693 hasAuthorship W2921668693A5041234325 @default.
• W2921668693 hasAuthorship W2921668693A5055648634 @default.
• W2921668693 hasAuthorship W2921668693A5056204835 @default.
• W2921668693 hasAuthorship W2921668693A5062814951 @default.
• W2921668693 hasAuthorship W2921668693A5072623319 @default.
• W2921668693 hasAuthorship W2921668693A5075596287 @default.
• W2921668693 hasAuthorship W2921668693A5079130521 @default.
• W2921668693 hasAuthorship W2921668693A5080347094 @default.
• W2921668693 hasAuthorship W2921668693A5085028391 @default.
• W2921668693 hasBestOaLocation W29216686931 @default.
• W2921668693 hasConcept C126322002 @default.
• W2921668693 hasConcept C142724271 @default.
• W2921668693 hasConcept C203014093 @default.
• W2921668693 hasConcept C2776036978 @default.
• W2921668693 hasConcept C2776819417 @default.
• W2921668693 hasConcept C2777703276 @default.
• W2921668693 hasConcept C2780640218 @default.
• W2921668693 hasConcept C2781156865 @default.

• next