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• W2921725323 abstract "Background: Occupational magnetic field (MF) exposure has been suggested as a male breast cancer risk factor, but due to the rarity of this disease, many epidemiologic studies investigating the relationship have been underpowered. As well, exploring this relationship in men provides an opportunity to overcome the potentially confounding influence of reproductive factors on this association in women. Aims: This study investigated associations of several characterizations of occupational MF exposure with male breast cancer using data from the population-based case-control component of the Canadian National Enhanced Cancer Surveillance System. Methods: Job histories were obtained for 115 cases and 570 controls. Using blinded expert review of each job, the average MF exposure of individual jobs was coded into three categories: <0.3, 0.3-<0.6 or ?0.6 µT. The impact of ever and cumulative MF exposure, as well as exposure duration and specific exposure-time windows, on cancer risk was examined using logistic regression adjusted for age, education, income, marital status, BMI and physical activity. Results: The proportion of cases (28%) who were ever exposed to ?0.3 µT was higher than among controls (22%) and an elevated, though not statistically significant, risk of breast cancer was seen in men ever exposed to ?0.6 µT (OR=1.81, 95%CI=0.81-4.03). Unadjusted analysis demonstrated a significantly increased risk for men with ?30 years of occupational MF exposure (OR=4.20, 95%CI=1.52-11.56), though this was attenuated after adjusting for other risk factors (OR=2.44, 95%CI=0.84-7.15). Conclusions: Our analysis, in one of the largest case-control studies of male breast cancer conducted to date, supports the idea that occupational exposure to MF increases breast cancer risk. The relatively wide confidence intervals underscore a research need to pool across multiple study populations to provide further insight into whether exposure to MF increases the risk of breast cancer." @default.
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• W2921725323 date "2013-09-19" @default.
• W2921725323 modified "2023-09-26" @default.
• W2921725323 title "Occupational Magnetic Field Exposure and Male Breast Cancer Among Canadian Men" @default.
• W2921725323 doi "https://doi.org/10.1289/isee.2013.p-3-21-11" @default.
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