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• W2921853268 abstract "Introduction: The incidence of neuroendocrine tumors(NETs) are increasing, especially in rectum. Hybrid endoscopic submucosal dissection(hybrid ESD), a method of simplifying the procedure of endoscopic submucosal dissection (ESD) with snaring, was reported that can achieve a shorter procedure time and similar safety for colorectal neoplasia. The purpose of this study was to evaluate the efficacy and safety of hybrid ESD compared with ESD for rectal NETs. Methods: This retrospective study included 220 patients with rectal NETs who underwent ESD or hybrid ESD at a single institution from November 2008 to December 2017. The relevant data were collected, en bloc resection rate, complete resection rate, procedure time, and incidence of complications were evaluated. Results: There were 127 patients with 132 lesions in the ESD group and 93 patients with 101 lesions in the hybrid ESD group, respectively. The en bloc resection rates in the hybrid ESD and the ESD group were similar(99.0% vs 97.7%; P=0.812),as were the complete resection rates(88.1% vs 81.8, P=0.187) and the postprocedural bleeding rates(2.0% vs 1.5%,P>0.999).There was no perforation in both groups. The mean procedure time was shorter in the hybrid ESD group compared with ESD group(13.04±7.84 vs 18.96±9.29, P<0.001). Conclusion: Hybrid ESD, compared with ESD, achieves similar en bloc resection rates, complete resection rates and adverse events rates, with a shorter procedure time for rectal NETs. Further techniques are required to improve the complete rates.772_A Figure 1. Flow chart of the study. 220 patients with 233 lesions were finally analyzed. ESD, endoscopic submucosal dissection.772_B Figure 2. ESD, Endoscopic submucosal dissection. N/A, not available. SD, standard deviation *All patients with multiple lesion type had two lesions.772_C Figure 3. ESD, Endoscopic submucosal dissection; N/A, not available; SD, standard deviation. Complete resection(curative resection) was defined as a resection leaving the vertical and lateral margins free of tumor (classified as R0). Incomplete resection(non-curative resection) was defined as a resection failing to achieve tumorfree margins (classified as R1), or a lesion with non-evaluable margins (classified as Rx) from a burn artifact or insufficient reconstruction of piecemeal fragments. Lymphovascular invasion was considered as incomplete histological resection. * In the ESD group, because of positive margins,1 patient underwent subsequent surgery, 1 patient underwent additional ESD." @default.
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• W2921853268 date "2018-10-01" @default.
• W2921853268 modified "2023-10-16" @default.
• W2921853268 title "Efficacy and Safety of Hybrid ESD for the Rectal Neuroendocrine Tumors: A Retrospective Study: Presidential Poster Award" @default.
• W2921853268 doi "https://doi.org/10.14309/00000434-201810001-00772" @default.
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