FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2921869941> ?p ?o ?g. }

• W2921869941 endingPage "1375" @default.
• W2921869941 startingPage "1367" @default.
• W2921869941 abstract "Early detection of altered epithelium can help in controlling the further progression by timely intervention. Alterations in cellular adhesion are one of the hallmarks of cancer progression, which can be detected at the intracellular level using high-resolution electron microscopy. This study aimed to evaluate the role of electron microscopy in the establishment of ultrastructural markers for early detection of altered epithelium using tissues from 4-Nitroquinoline-1-Oxide (4NQO) induced rat tongue carcinogenesis. Our previous study using light microscopy displayed no histopathological alterations in 4NQO treated tissues until 40 days of treatment, while dysplasia, papilloma and carcinoma were detected at 80/120, 160 and 200 days, respectively. However, electron microscopy detected alterations such as detachment of desmosomes from cell membranes and their clustering in the cytoplasm, increased tonofilaments, keratohyaline granules and thickened corneum in 40 days treated corresponding tissues. These alterations are apparent with hyperkeratosis/hyperplasia but remained undetected using light microscopy. Further, in dysplasia, papilloma and carcinoma, gradual and significant loss of desmosomes, leading to the significant widening of intercellular spaces, was observed using iTEM software. These parameters may serve as indicators for progression of oral cancer. Our results highlight the importance of electron microscopy in the early detection of subcellular changes in the altered epithelium." @default.
• W2921869941 created "2019-03-22" @default.
• W2921869941 creator A5010241998 @default.
• W2921869941 creator A5015595879 @default.
• W2921869941 creator A5027197978 @default.
• W2921869941 creator A5032599204 @default.
• W2921869941 creator A5040003982 @default.
• W2921869941 creator A5051659974 @default.
• W2921869941 date "2019-03-14" @default.
• W2921869941 modified "2023-10-14" @default.
• W2921869941 title "Role of Electron Microscopy in Early Detection of Altered Epithelium During Experimental Oral Carcinogenesis" @default.
• W2921869941 cites W1973997059 @default.
• W2921869941 cites W1980514342 @default.
• W2921869941 cites W2001764259 @default.
• W2921869941 cites W2005047241 @default.
• W2921869941 cites W2010778733 @default.
• W2921869941 cites W2024090481 @default.
• W2921869941 cites W2024156824 @default.
• W2921869941 cites W2033163411 @default.
• W2921869941 cites W2036858312 @default.
• W2921869941 cites W2040213637 @default.
• W2921869941 cites W2064573184 @default.
• W2921869941 cites W2069586471 @default.
• W2921869941 cites W2094333541 @default.
• W2921869941 cites W2127765487 @default.
• W2921869941 cites W2141549067 @default.
• W2921869941 cites W2145587555 @default.
• W2921869941 cites W2158108125 @default.
• W2921869941 cites W2159247973 @default.
• W2921869941 cites W2169851453 @default.
• W2921869941 cites W2333780071 @default.
• W2921869941 cites W2480325303 @default.
• W2921869941 cites W2587964183 @default.
• W2921869941 cites W2796762284 @default.
• W2921869941 cites W2807926766 @default.
• W2921869941 cites W39042124 @default.
• W2921869941 cites W4232058283 @default.
• W2921869941 cites W4299300060 @default.
• W2921869941 doi "https://doi.org/10.1017/s1431927619000229" @default.
• W2921869941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30867083" @default.
• W2921869941 hasPublicationYear "2019" @default.
• W2921869941 type Work @default.
• W2921869941 sameAs 2921869941 @default.
• W2921869941 citedByCount "4" @default.
• W2921869941 countsByYear W29218699412021 @default.
• W2921869941 countsByYear W29218699412022 @default.
• W2921869941 crossrefType "journal-article" @default.
• W2921869941 hasAuthorship W2921869941A5010241998 @default.
• W2921869941 hasAuthorship W2921869941A5015595879 @default.
• W2921869941 hasAuthorship W2921869941A5027197978 @default.
• W2921869941 hasAuthorship W2921869941A5032599204 @default.
• W2921869941 hasAuthorship W2921869941A5040003982 @default.
• W2921869941 hasAuthorship W2921869941A5051659974 @default.
• W2921869941 hasBestOaLocation W29218699411 @default.
• W2921869941 hasConcept C120665830 @default.
• W2921869941 hasConcept C121332964 @default.
• W2921869941 hasConcept C121608353 @default.
• W2921869941 hasConcept C142724271 @default.
• W2921869941 hasConcept C147080431 @default.
• W2921869941 hasConcept C185592680 @default.
• W2921869941 hasConcept C190062978 @default.
• W2921869941 hasConcept C2775894508 @default.
• W2921869941 hasConcept C2776350393 @default.
• W2921869941 hasConcept C529295009 @default.
• W2921869941 hasConcept C54355233 @default.
• W2921869941 hasConcept C555283112 @default.
• W2921869941 hasConcept C71924100 @default.
• W2921869941 hasConcept C86803240 @default.
• W2921869941 hasConcept C87555872 @default.
• W2921869941 hasConcept C93877712 @default.
• W2921869941 hasConcept C95444343 @default.
• W2921869941 hasConceptScore W2921869941C120665830 @default.
• W2921869941 hasConceptScore W2921869941C121332964 @default.
• W2921869941 hasConceptScore W2921869941C121608353 @default.
• W2921869941 hasConceptScore W2921869941C142724271 @default.
• W2921869941 hasConceptScore W2921869941C147080431 @default.
• W2921869941 hasConceptScore W2921869941C185592680 @default.
• W2921869941 hasConceptScore W2921869941C190062978 @default.
• W2921869941 hasConceptScore W2921869941C2775894508 @default.
• W2921869941 hasConceptScore W2921869941C2776350393 @default.
• W2921869941 hasConceptScore W2921869941C529295009 @default.
• W2921869941 hasConceptScore W2921869941C54355233 @default.
• W2921869941 hasConceptScore W2921869941C555283112 @default.
• W2921869941 hasConceptScore W2921869941C71924100 @default.
• W2921869941 hasConceptScore W2921869941C86803240 @default.
• W2921869941 hasConceptScore W2921869941C87555872 @default.
• W2921869941 hasConceptScore W2921869941C93877712 @default.
• W2921869941 hasConceptScore W2921869941C95444343 @default.
• W2921869941 hasIssue "6" @default.
• W2921869941 hasLocation W29218699411 @default.
• W2921869941 hasLocation W29218699412 @default.
• W2921869941 hasOpenAccess W2921869941 @default.
• W2921869941 hasPrimaryLocation W29218699411 @default.
• W2921869941 hasRelatedWork W1545303776 @default.
• W2921869941 hasRelatedWork W2069143777 @default.
• W2921869941 hasRelatedWork W2082895746 @default.
• W2921869941 hasRelatedWork W2102214307 @default.
• W2921869941 hasRelatedWork W2115183286 @default.

• next