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- W2922132368 abstract "Although antiretroviral therapy (ART) is highly successful, drug-resistant variants can arise that blunt the efficacy of ART. New inhibitors that are broadly effective against known drug-resistant variants are needed, although such compounds might select for novel resistance mutations that affect the sensitivity of the virus to other compounds. Compound 13 selects for resistance mutations that differ from traditional NNRTI resistance mutations. These mutations cause increased sensitivity to NRTIs, such as AZT." @default.
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- W2922132368 date "2019-06-01" @default.
- W2922132368 modified "2023-10-16" @default.
- W2922132368 title "Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs" @default.
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- W2922132368 doi "https://doi.org/10.1128/jvi.00224-19" @default.
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