Matches in SemOpenAlex for { <https://semopenalex.org/work/W2922142409> ?p ?o ?g. }
- W2922142409 endingPage "76" @default.
- W2922142409 startingPage "62" @default.
- W2922142409 abstract "In vertebrates, double-strand breaks in DNA are primarily repaired by Non-Homologous End-Joining (NHEJ). The ring-shaped Ku heterodimer rapidly senses and threads onto broken DNA ends forming a recruiting hub. Through protein-protein contacts eventually reinforced by protein-DNA interactions, the Ku-DNA hub attracts a series of specialized proteins with scaffolding and/or enzymatic properties. To shed light on these dynamic interplays, we review here current knowledge on proteins directly interacting with Ku and on the contact points involved, with a particular accent on the different classes of Ku-binding motifs identified in several Ku partners. An integrated structural model of the core NHEJ network at the synapsis step is proposed." @default.
- W2922142409 created "2019-03-22" @default.
- W2922142409 creator A5038479758 @default.
- W2922142409 creator A5056164519 @default.
- W2922142409 creator A5058213120 @default.
- W2922142409 creator A5071142299 @default.
- W2922142409 creator A5080266934 @default.
- W2922142409 date "2019-10-01" @default.
- W2922142409 modified "2023-10-18" @default.
- W2922142409 title "Plugged into the Ku-DNA hub: The NHEJ network" @default.
- W2922142409 cites W1516845708 @default.
- W2922142409 cites W1529783938 @default.
- W2922142409 cites W1557970645 @default.
- W2922142409 cites W1838945435 @default.
- W2922142409 cites W1861478519 @default.
- W2922142409 cites W1897299346 @default.
- W2922142409 cites W1940074648 @default.
- W2922142409 cites W1963613246 @default.
- W2922142409 cites W1966254852 @default.
- W2922142409 cites W1969424502 @default.
- W2922142409 cites W1977145510 @default.
- W2922142409 cites W1978417963 @default.
- W2922142409 cites W1984886867 @default.
- W2922142409 cites W1985363523 @default.
- W2922142409 cites W1985643620 @default.
- W2922142409 cites W1986446154 @default.
- W2922142409 cites W1986830781 @default.
- W2922142409 cites W1989926983 @default.
- W2922142409 cites W1992688638 @default.
- W2922142409 cites W1995796643 @default.
- W2922142409 cites W1996296667 @default.
- W2922142409 cites W1997576768 @default.
- W2922142409 cites W2000039654 @default.
- W2922142409 cites W2000438077 @default.
- W2922142409 cites W2001762032 @default.
- W2922142409 cites W2001784394 @default.
- W2922142409 cites W2004575615 @default.
- W2922142409 cites W2006322108 @default.
- W2922142409 cites W2008415057 @default.
- W2922142409 cites W2008605706 @default.
- W2922142409 cites W2008864694 @default.
- W2922142409 cites W2013534397 @default.
- W2922142409 cites W2013580891 @default.
- W2922142409 cites W2013703669 @default.
- W2922142409 cites W2017550130 @default.
- W2922142409 cites W2018016223 @default.
- W2922142409 cites W2019571003 @default.
- W2922142409 cites W2021314470 @default.
- W2922142409 cites W2022773650 @default.
- W2922142409 cites W2023324317 @default.
- W2922142409 cites W2024164424 @default.
- W2922142409 cites W2025997331 @default.
- W2922142409 cites W2028128317 @default.
- W2922142409 cites W2032067907 @default.
- W2922142409 cites W2033270381 @default.
- W2922142409 cites W2038596673 @default.
- W2922142409 cites W2038875604 @default.
- W2922142409 cites W2039547989 @default.
- W2922142409 cites W2040847982 @default.
- W2922142409 cites W2041286364 @default.
- W2922142409 cites W2041529030 @default.
- W2922142409 cites W2046592596 @default.
- W2922142409 cites W2047108906 @default.
- W2922142409 cites W2048250731 @default.
- W2922142409 cites W2048342686 @default.
- W2922142409 cites W2048916500 @default.
- W2922142409 cites W2049018115 @default.
- W2922142409 cites W2049027585 @default.
- W2922142409 cites W2049878642 @default.
- W2922142409 cites W2051148032 @default.
- W2922142409 cites W2052349609 @default.
- W2922142409 cites W2053405779 @default.
- W2922142409 cites W2056060176 @default.
- W2922142409 cites W2056406429 @default.
- W2922142409 cites W2061015483 @default.
- W2922142409 cites W2061060103 @default.
- W2922142409 cites W2067982379 @default.
- W2922142409 cites W2068140359 @default.
- W2922142409 cites W2070395126 @default.
- W2922142409 cites W2071206740 @default.
- W2922142409 cites W2071695004 @default.
- W2922142409 cites W2072322720 @default.
- W2922142409 cites W2075351905 @default.
- W2922142409 cites W2076798160 @default.
- W2922142409 cites W2078288351 @default.
- W2922142409 cites W2078591866 @default.
- W2922142409 cites W2084919692 @default.
- W2922142409 cites W2085422820 @default.
- W2922142409 cites W2089138444 @default.
- W2922142409 cites W2092470694 @default.
- W2922142409 cites W2094046881 @default.
- W2922142409 cites W2095687796 @default.
- W2922142409 cites W2100518470 @default.
- W2922142409 cites W2101281834 @default.
- W2922142409 cites W2102329938 @default.
- W2922142409 cites W2102757030 @default.
- W2922142409 cites W2104844303 @default.
- W2922142409 cites W2109272669 @default.