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- W2922144439 abstract "Objective To study the characteristics of esophageal motility in the patients with different symptoms of nonerosive reflux disease (non-erosive reflux disease, NERD). Methods Eighty-six patients with NERD who visited the Department of Gastroenterology in our hospital from August 2012 to December 2014 were selected. They were all evaluated with upper gastrointestinal endoscopy and high resolution esophageal manometry. Those who had neither definite esophageal mucosal erosion nor Barrett's esophagus at endoscopy were diagnosed as NERD. According to the presence or absence of typical acid reflux and/or heartburn symptoms, patients with NERD were divided into two groups: the typical symptom group (47 cases), and the atypical symptom group (39 cases). High resolution measurement of esophageal pressure was used to evaluate the differences in esophageal dynamic characteristics between patients with different symptoms of NERD. The final results were analyzed with t test and chi-square test. Results Compared with atypical symptom group, both the resting pressure (20.68±1.64mmHg vs 15.79±1.21mmHg respectively, P 0.05). Conclusion There is a difference in esophageal motility characteristics between the patients with typical and atypical symptoms of NERD, and the main differences are changes in the resting pressure and residual pressure of LES.DOI: 10.11855/j.issn.0577-7402.2015.12.12" @default.
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- W2922144439 date "2015-12-01" @default.
- W2922144439 modified "2023-09-26" @default.
- W2922144439 title "The differences in esophageal motility and its clinical significance between the patients with typical and atypical symptoms of non-erosive reflux disease" @default.
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