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• W2922153917 abstract "Lactobacillus is widely studied for prevention and treatment of intestinal diseases. The study was conducted to determine anti-inflammatory and antioxidative potential of Lactobacillus plantarum 1.2567 using necrotic enteritis (NES) model of broiler chickens caused by Clostridium perfringens. A total of 288 one-day-old broiler chickens were randomly categorized into 4 treatments: CON (basal diet), NES (CON + C. perfringens), LPT (NES + L. plantarum1.2567 powder with skim milk) and SKT (NES + skim milk). Results showed that L. plantarum 1.2567 increased average daily gain of the challenged broiler chickens (P< 0.05), reduced gross lesion scores of the small intestines and ameliorated ileum histopathology (P< 0.05), improved structure of enterocyte microvilli (P< 0.001), attenuated the nitric oxide concentration and myeloperoxidase activity (P< 0.05), reduced the chTNF-α and IL-1β levels and enhanced the activity of SOD and CAT(P< 0.05), and decreased MDA content (P< 0.05). But skim milk only improved structure of enterocyte microvilli of the challenged broiler chickens (P< 0.05). In conclusion, L. plantarum 1.2567 is a promising tool to control NES by regulating the intestinal mucosal immune response, and improving villi structure and antioxidant defense system in broiler chickens." @default.
• W2922153917 created "2019-03-22" @default.
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• W2922153917 date "2019-05-01" @default.
• W2922153917 modified "2023-09-24" @default.
• W2922153917 title "Anti-inflammatory and antioxidant activities of probiotic powder containing Lactobacillus plantarum 1.2567 in necrotic enteritis model of broiler chickens" @default.
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• W2922153917 doi "https://doi.org/10.1016/j.livsci.2019.03.009" @default.
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