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- W2922171446 abstract "### Key learning pointsChronic pain affects up to 30% of the Western population with a prevalence higher than any other chronic disease.1 Chronic pain is often of a non-specific nature, implying that there is no tissue damage, or that tissue damage is not severe enough to explain the pain experience and/or related symptoms. This non-specific nature accounts for non-cancer pain as well as post-cancer pain (ie, pain in cancer survivors). Chronic pain has a significant personal and socioeconomic impact: among long-term conditions, it is responsible for the highest number of years lived with disability and is the most expensive cause of work-related disability.2–4 Chronic pain also decreases life expectancy, in part due to excess deaths from cancer and cardiovascular disease.5–7 Over the past decades, neuroscience has advanced our understanding about pain, including the role of CNS sensitisation—more briefly termed central sensitisation (CS). The original definition for CS—‘an amplification of neural signaling within the CNS that elicits pain hypersensitivity’—originated from laboratory research, but nowadays the chronic pain management field has more or less …" @default.
- W2922171446 created "2019-03-22" @default.
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- W2922171446 date "2019-03-11" @default.
- W2922171446 modified "2023-10-17" @default.
- W2922171446 title "Central sensitisation: another label or useful diagnosis?" @default.
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- W2922171446 doi "https://doi.org/10.1136/dtb.2018.000035" @default.
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