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• W2922188418 startingPage "1236" @default.
• W2922188418 abstract "Lipase RMIM was firstly used as a promiscuous biocatalyst to catalyze the Knoevenagel-Michael cascade reactions of 4-hydroxycoumarin with aromatic, heterocyclic or aliphatic aldehydes to synthesize dicoumarol derivatives in water. Results showed that the adopted methodology could offer many advantages, such as mild reaction conditions, pure aqueous reaction system, wide substrate applicability, recyclable catalyst, excellent yields (81–98%), operational simplicity, and environmentally friendly reactions." @default.
• W2922188418 created "2019-03-22" @default.
• W2922188418 creator A5026954484 @default.
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• W2922188418 date "2019-05-01" @default.
• W2922188418 modified "2023-09-23" @default.
• W2922188418 title "Promiscuous enzyme-catalyzed cascade reaction in water: Synthesis of dicoumarol derivatives" @default.
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• W2922188418 doi "https://doi.org/10.1016/j.bmcl.2019.03.007" @default.
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