FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2922196352> ?p ?o ?g. }

• W2922196352 endingPage "646" @default.
• W2922196352 startingPage "640" @default.
• W2922196352 abstract "Nasal reconstruction is limited by the availability of autologous cartilage. The aim is to investigate an adhesive biomaterial for tissue engineering of nasal cartilage by evaluating mechanical properties of hydrogels made of fibrin crosslinked with genipin as compared to native tissue.Hydrogels of fibrin, fibrin-genipin, and fibrin-genipin with extracellular matrix (ECM) particles were created and evaluated with mechanical testing to determine compression, tensile, and shear properties. Rabbit nasal septal cartilage was harvested and tested in these modalities for comparison. Transmission electron microscopy characterized hydrogel structure.Fibrin-genipin gels had higher compressive, tensile, and shear moduli compared to fibrin alone or fibrin-genipin with ECM. However, all hydrogel formulations had lower moduli than the rabbit nasal septal cartilage. Electron microscopy showed genipin crosslinking increased structural density of the hydrogel and that cartilage ECM created larger structural features with lower crosslinking density.The addition of genipin significantly improved mechanical properties of fibrin hydrogels by increasing the compressive, tensile, and shear moduli. The addition of cartilage ECM, which can add native structure and composition, resulted in decreased moduli values. Fibrin-genipin is a bioactive and biomechanically stable hydrogel that may offer promise as a scaffold for cartilage tissue engineering in nasal reconstruction, yet further augmentation is required to match material properties of native nasal cartilage." @default.
• W2922196352 created "2019-03-22" @default.
• W2922196352 creator A5003784305 @default.
• W2922196352 creator A5005963410 @default.
• W2922196352 creator A5006081657 @default.
• W2922196352 creator A5066933752 @default.
• W2922196352 creator A5082951214 @default.
• W2922196352 date "2019-03-12" @default.
• W2922196352 modified "2023-10-14" @default.
• W2922196352 title "Fibrin-Genipin Hydrogel for Cartilage Tissue Engineering in Nasal Reconstruction" @default.
• W2922196352 cites W1994537168 @default.
• W2922196352 cites W2012239558 @default.
• W2922196352 cites W2018611464 @default.
• W2922196352 cites W2041162832 @default.
• W2922196352 cites W2066517877 @default.
• W2922196352 cites W2067459499 @default.
• W2922196352 cites W2081189577 @default.
• W2922196352 cites W2093820413 @default.
• W2922196352 cites W2097228866 @default.
• W2922196352 cites W2131137708 @default.
• W2922196352 cites W2165780899 @default.
• W2922196352 cites W2191225761 @default.
• W2922196352 cites W2418473818 @default.
• W2922196352 cites W2497885527 @default.
• W2922196352 cites W2529988936 @default.
• W2922196352 cites W2558128026 @default.
• W2922196352 cites W2567216580 @default.
• W2922196352 cites W2596475650 @default.
• W2922196352 cites W77641063 @default.
• W2922196352 cites W782841224 @default.
• W2922196352 cites W2061779521 @default.
• W2922196352 doi "https://doi.org/10.1177/0003489419836667" @default.
• W2922196352 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6538487" @default.
• W2922196352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30862177" @default.
• W2922196352 hasPublicationYear "2019" @default.
• W2922196352 type Work @default.
• W2922196352 sameAs 2922196352 @default.
• W2922196352 citedByCount "21" @default.
• W2922196352 countsByYear W29221963522019 @default.
• W2922196352 countsByYear W29221963522020 @default.
• W2922196352 countsByYear W29221963522021 @default.
• W2922196352 countsByYear W29221963522022 @default.
• W2922196352 countsByYear W29221963522023 @default.
• W2922196352 crossrefType "journal-article" @default.
• W2922196352 hasAuthorship W2922196352A5003784305 @default.
• W2922196352 hasAuthorship W2922196352A5005963410 @default.
• W2922196352 hasAuthorship W2922196352A5006081657 @default.
• W2922196352 hasAuthorship W2922196352A5066933752 @default.
• W2922196352 hasAuthorship W2922196352A5082951214 @default.
• W2922196352 hasBestOaLocation W29221963522 @default.
• W2922196352 hasConcept C105702510 @default.
• W2922196352 hasConcept C108586683 @default.
• W2922196352 hasConcept C112950240 @default.
• W2922196352 hasConcept C136229726 @default.
• W2922196352 hasConcept C159985019 @default.
• W2922196352 hasConcept C185592680 @default.
• W2922196352 hasConcept C188027245 @default.
• W2922196352 hasConcept C189165786 @default.
• W2922196352 hasConcept C192562407 @default.
• W2922196352 hasConcept C203014093 @default.
• W2922196352 hasConcept C2779732960 @default.
• W2922196352 hasConcept C2780550940 @default.
• W2922196352 hasConcept C2781438746 @default.
• W2922196352 hasConcept C49892992 @default.
• W2922196352 hasConcept C54173615 @default.
• W2922196352 hasConcept C55493867 @default.
• W2922196352 hasConcept C71924100 @default.
• W2922196352 hasConceptScore W2922196352C105702510 @default.
• W2922196352 hasConceptScore W2922196352C108586683 @default.
• W2922196352 hasConceptScore W2922196352C112950240 @default.
• W2922196352 hasConceptScore W2922196352C136229726 @default.
• W2922196352 hasConceptScore W2922196352C159985019 @default.
• W2922196352 hasConceptScore W2922196352C185592680 @default.
• W2922196352 hasConceptScore W2922196352C188027245 @default.
• W2922196352 hasConceptScore W2922196352C189165786 @default.
• W2922196352 hasConceptScore W2922196352C192562407 @default.
• W2922196352 hasConceptScore W2922196352C203014093 @default.
• W2922196352 hasConceptScore W2922196352C2779732960 @default.
• W2922196352 hasConceptScore W2922196352C2780550940 @default.
• W2922196352 hasConceptScore W2922196352C2781438746 @default.
• W2922196352 hasConceptScore W2922196352C49892992 @default.
• W2922196352 hasConceptScore W2922196352C54173615 @default.
• W2922196352 hasConceptScore W2922196352C55493867 @default.
• W2922196352 hasConceptScore W2922196352C71924100 @default.
• W2922196352 hasFunder F4320337362 @default.
• W2922196352 hasIssue "7" @default.
• W2922196352 hasLocation W29221963521 @default.
• W2922196352 hasLocation W29221963522 @default.
• W2922196352 hasLocation W29221963523 @default.
• W2922196352 hasOpenAccess W2922196352 @default.
• W2922196352 hasPrimaryLocation W29221963521 @default.
• W2922196352 hasRelatedWork W1483284319 @default.
• W2922196352 hasRelatedWork W1820377529 @default.
• W2922196352 hasRelatedWork W1978262597 @default.
• W2922196352 hasRelatedWork W2031937320 @default.
• W2922196352 hasRelatedWork W2115136548 @default.
• W2922196352 hasRelatedWork W2151149598 @default.
• W2922196352 hasRelatedWork W2933891664 @default.

• next