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• W2922275988 abstract "Chagas disease is the highest impact parasitic disease in Latin America. In recent years, the use of immune-related biomarkers to predict diagnostic and treatment efficacy or to monitor diseases has been considered a promising tool. Our group has worked for the past 20 years on the characterization of different immunological aspects of the T-cell responses to T. cruzi antigens. We have shown that monitoring of appropriate immunological responses can provide earlier and robust measures of treatment.The Enzyme-Linked ImmunoSPOT (ELISPOT) assays are powerful tools to evaluate antigen-specific immune responses at the single-cell level. Herein, we describe uses of the ELISPOT assay to determine the T. cruzi-specific T-cell populations in PBMCs from chronic chagasic subjects." @default.
• W2922275988 created "2019-03-22" @default.
• W2922275988 creator A5004140042 @default.
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• W2922275988 date "2019-01-01" @default.
• W2922275988 modified "2023-09-25" @default.
• W2922275988 title "Trypanosoma cruzi-Specific T-Cell Responses to Monitor Treatment Efficacy in Chronic Chagas Disease" @default.
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• W2922275988 doi "https://doi.org/10.1007/978-1-4939-9148-8_25" @default.
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• W2922275988 hasPublicationYear "2019" @default.
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