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• W2922307005 abstract "As an alternative to conventional liquid-liquid extraction (LLE), The supported liquid extraction (SLE) employs diatomaceous earth as solid support on which analytes can be partitioned between aqueous and water immiscible solvents. SLE alleviates many liquid handling issues related to LLE such as emulsion formation. Nowadays, SLE is commercially available in plate and cartridge formats. Compared to LLE, SLE provides more efficient extraction and more options for solvent selection. Phospholipids removal using SLE leads to a better assay performance by minimizing potential matrix effect. This technology has been implemented in a wide range of applications including pharmacokinetics, toxicokinetics, clinical study support, endogenous components analysis, doping control, drugs of abuse testing and forensic toxicological analysis, etc." @default.
• W2922307005 created "2019-03-22" @default.
• W2922307005 creator A5028291486 @default.
• W2922307005 creator A5084640582 @default.
• W2922307005 date "2019-02-25" @default.
• W2922307005 modified "2023-10-18" @default.
• W2922307005 title "Supported Liquid Extraction (SLE) in LC‐MS Bioanalysis" @default.
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• W2922307005 doi "https://doi.org/10.1002/9781119274315.ch6" @default.
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