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- W2922319076 endingPage "1151" @default.
- W2922319076 startingPage "1140" @default.
- W2922319076 abstract "Clinical investigations in inflammatory bowel disease (IBD) patients have provided increasing evidence that eosinophils contribute to chronic intestinal inflammation. Accumulation of eosinophils in the gastrointestinal tract correlates with the variations of eosinophil regulatory molecules; however, their role in gastrointestinal dysfunction in IBD has not been fully elucidated. This review will describe the development and characterization of gastrointestinal eosinophils, mechanisms of eosinophil recruitment to the gastrointestinal tract. Moreover, the eosinophil-induced changes to the enteric nervous system associated with disease severity and gastrointestinal dysfunction will be analyzed with suggestive molecular pathways for enteric neuronal injury. Current and potential therapeutic interventions targeting eosinophils will be discussed." @default.
- W2922319076 created "2019-03-22" @default.
- W2922319076 creator A5045186655 @default.
- W2922319076 creator A5051380014 @default.
- W2922319076 creator A5076471787 @default.
- W2922319076 creator A5083999303 @default.
- W2922319076 date "2019-03-11" @default.
- W2922319076 modified "2023-10-17" @default.
- W2922319076 title "Eosinophils in Inflammatory Bowel Disease" @default.
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