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• W2922365089 endingPage "2345" @default.
• W2922365089 startingPage "2336" @default.
• W2922365089 abstract "Brain and heart ischemia are among the leading causes of death and disability in both men and women, but there are significant sex differences in the incidence and severity of these diseases. Ca2+ dysregulation in response to ischemia/reperfusion injury (I/RI) is a well-recognized pathogenic mechanism leading to the death of affected cells. Excess intracellular Ca2+ causes mitochondrial matrix Ca2+ overload that can result in mitochondrial permeability transition (MPT), which can have severe consequences for mitochondrial function and trigger cell death. Recent findings indicate that estrogens and their related receptors are involved in the regulation of MPT, suggesting that sex differences in I/RI could be linked to estrogen-dependent modulation of mitochondrial Ca2+. Here, we review the evidence supporting sex differences in I/RI and the role of estrogen and estrogen receptors in producing these differences, the involvement of mitochondrial Ca2+ overload in disease pathogenesis, and the estrogen-dependent modulation of MPT that may contribute to sex differences." @default.
• W2922365089 created "2019-03-22" @default.
• W2922365089 creator A5051379190 @default.
• W2922365089 creator A5068204379 @default.
• W2922365089 date "2019-03-12" @default.
• W2922365089 modified "2023-10-12" @default.
• W2922365089 title "Sex Differences in Ischemia/Reperfusion Injury: The Role of Mitochondrial Permeability Transition" @default.
• W2922365089 cites W1496281435 @default.
• W2922365089 cites W1500536335 @default.
• W2922365089 cites W1504822816 @default.
• W2922365089 cites W1562324545 @default.
• W2922365089 cites W1564601025 @default.
• W2922365089 cites W1566485317 @default.
• W2922365089 cites W1598578622 @default.
• W2922365089 cites W1603109630 @default.
• W2922365089 cites W1639407471 @default.
• W2922365089 cites W1961319082 @default.
• W2922365089 cites W1966038248 @default.
• W2922365089 cites W1966069684 @default.
• W2922365089 cites W1968112618 @default.
• W2922365089 cites W1968257316 @default.
• W2922365089 cites W1971510102 @default.
• W2922365089 cites W1971608015 @default.
• W2922365089 cites W1972681977 @default.
• W2922365089 cites W1976348423 @default.
• W2922365089 cites W1976835482 @default.
• W2922365089 cites W1981478938 @default.
• W2922365089 cites W1981483033 @default.
• W2922365089 cites W1986957275 @default.
• W2922365089 cites W1990477938 @default.
• W2922365089 cites W1990646008 @default.
• W2922365089 cites W1991307433 @default.
• W2922365089 cites W1993039541 @default.
• W2922365089 cites W1994442108 @default.
• W2922365089 cites W1996907401 @default.
• W2922365089 cites W2000864465 @default.
• W2922365089 cites W2002439304 @default.
• W2922365089 cites W2003064131 @default.
• W2922365089 cites W2006786051 @default.
• W2922365089 cites W2008757109 @default.
• W2922365089 cites W2011629756 @default.
• W2922365089 cites W2016373832 @default.
• W2922365089 cites W2017357941 @default.
• W2922365089 cites W2018090541 @default.
• W2922365089 cites W2018776448 @default.
• W2922365089 cites W2020178087 @default.
• W2922365089 cites W2021612112 @default.
• W2922365089 cites W2025077643 @default.
• W2922365089 cites W2025624761 @default.
• W2922365089 cites W2028023732 @default.
• W2922365089 cites W2028155268 @default.
• W2922365089 cites W2035219321 @default.
• W2922365089 cites W2037676584 @default.
• W2922365089 cites W2052737683 @default.
• W2922365089 cites W2058013358 @default.
• W2922365089 cites W2061460906 @default.
• W2922365089 cites W2061710435 @default.
• W2922365089 cites W2063099262 @default.
• W2922365089 cites W2063385957 @default.
• W2922365089 cites W2063585967 @default.
• W2922365089 cites W2063830130 @default.
• W2922365089 cites W2064629195 @default.
• W2922365089 cites W2065236743 @default.
• W2922365089 cites W2066200217 @default.
• W2922365089 cites W2068976528 @default.
• W2922365089 cites W2073965098 @default.
• W2922365089 cites W2074800090 @default.
• W2922365089 cites W2075026191 @default.
• W2922365089 cites W2075443169 @default.
• W2922365089 cites W2076135266 @default.
• W2922365089 cites W2079781432 @default.
• W2922365089 cites W2085579135 @default.
• W2922365089 cites W2085935734 @default.
• W2922365089 cites W2088629175 @default.
• W2922365089 cites W2088963243 @default.
• W2922365089 cites W2091097006 @default.
• W2922365089 cites W2091300408 @default.
• W2922365089 cites W2095234263 @default.
• W2922365089 cites W2102557050 @default.
• W2922365089 cites W2105541649 @default.
• W2922365089 cites W2111364175 @default.
• W2922365089 cites W2116110451 @default.
• W2922365089 cites W2116415746 @default.
• W2922365089 cites W2116444561 @default.
• W2922365089 cites W2119740996 @default.
• W2922365089 cites W2125775109 @default.
• W2922365089 cites W2131850574 @default.
• W2922365089 cites W2134545202 @default.
• W2922365089 cites W2142403061 @default.
• W2922365089 cites W2147524524 @default.
• W2922365089 cites W2147529186 @default.
• W2922365089 cites W2149685553 @default.
• W2922365089 cites W2150509483 @default.
• W2922365089 cites W2151524159 @default.
• W2922365089 cites W2151634337 @default.
• W2922365089 cites W2159984609 @default.
• W2922365089 cites W2169995490 @default.
• W2922365089 cites W2170597525 @default.

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