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• W2922372425 abstract "Abstract Objective To compare estimates of gastric accommodation (GA) with single photon emission computed tomography (SPECT) to measurements based on intragastric meal distribution immediately post‐meal ingestion (IMD 0 ). Methods We evaluated 108 diabetics with upper gastrointestinal (UGI) symptoms who had undergone gastric emptying of solids (GE) by scintigraphy and GA measurements by SPECT. Immediately after ingestion of a 99m Tc‐labeled egg meal (time 0), we estimated IMD 0 as radioactive counts or area of the proximal half of the stomach on two‐dimensional images. Gastric volume (GV) during fasting and after 300 mL Ensure ® was measured by SPECT to quantify accommodation volume (AV) or postprandial to fasting volume ratio (GVR). From the measured proximal gastric area, we estimated the volume of proximal stomach (4/3 × π × r 3 ). We performed regression analyses to assess relationships between IMD 0 and GA (AV) and GVR. Results There was a significant correlation between area and radioactivity counts in the proximal stomach ( r = 0.67, P < 0.001); however, there was considerable interpersonal variation [bias 0.20 (95% CI −0.07, 0.47)]. There were no significant correlations between total GV or AV or VR by SPECT and measurements using IMD 0 : proximal gastric counts, area, and estimated volume as continuous variables of dichotomized patient groups, based on published cutoff values. There were no significant differences in total gastric area or the IMD 0 parameters (% area or % radioactive counts) between those with and without UGI symptoms except for fullness and satiety. Conclusions Intragastric meal distribution immediately post‐meal ingestion is not significantly correlated with GA measurement by SPECT." @default.
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• W2922372425 date "2019-03-13" @default.
• W2922372425 modified "2023-09-30" @default.
• W2922372425 title "Gastric accommodation measurements by single photon emission computed tomography and two‐dimensional scintigraphy in diabetic patients with upper gastrointestinal symptoms" @default.
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• W2922372425 doi "https://doi.org/10.1111/nmo.13581" @default.
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