Matches in SemOpenAlex for { <https://semopenalex.org/work/W2922493357> ?p ?o ?g. }
- W2922493357 abstract "Fibronectin (FN) type III domain containing 3B (FNDC3B), a member of the FN family, regulates the invasion and metastasis of cells in numerous tumor types. However, the mechanisms through which FNDC3B regulates carcinogenesis in lung adenocarcinoma (LADC) tissues have remained elusive. The present study revealed that the protein levels of FNDC3B and vimentin were significantly elevated in LADC tissues compared with those in normal lung tissues. By contrast, the expression of E-cadherin was decreased in LADC tissues compared with that in normal lung tissues. Furthermore, the aberrant expression of FNDC3B and epithelial-mesenchymal transition (EMT) markers was significantly associated with histological differentiation, lymph node metastasis and tumor-nodes-metastasis stage. Kaplan-Meier analysis indicated that a high expression of FNDC3B may be associated with poor overall survival of patients with LADC. In addition, overexpression of FNDC3B promoted the protein expression of EMT-associated genes in the A549 lung adenocarcinoma cell line. In conclusion, the present results support the notion that FNDC3B acts as an oncogene in LADC; it may serve a pivotal role in the development and progression of LADC and may participate in the regulation of the EMT." @default.
- W2922493357 created "2019-03-22" @default.
- W2922493357 creator A5000214013 @default.
- W2922493357 creator A5005268649 @default.
- W2922493357 creator A5014942240 @default.
- W2922493357 creator A5018411567 @default.
- W2922493357 creator A5021889091 @default.
- W2922493357 creator A5034453700 @default.
- W2922493357 creator A5037995990 @default.
- W2922493357 creator A5041937683 @default.
- W2922493357 creator A5060165452 @default.
- W2922493357 creator A5080110690 @default.
- W2922493357 creator A5090818171 @default.
- W2922493357 date "2019-03-12" @default.
- W2922493357 modified "2023-10-18" @default.
- W2922493357 title "Overexpression of fibronectin type�III domain containing�3B is correlated with epithelial‑mesenchymal transition and predicts poor prognosis in lung adenocarcinoma" @default.
- W2922493357 cites W1458965790 @default.
- W2922493357 cites W1933552182 @default.
- W2922493357 cites W1971078401 @default.
- W2922493357 cites W1974374404 @default.
- W2922493357 cites W1994758057 @default.
- W2922493357 cites W2012478368 @default.
- W2922493357 cites W2012664883 @default.
- W2922493357 cites W2016190772 @default.
- W2922493357 cites W2034531741 @default.
- W2922493357 cites W2040750718 @default.
- W2922493357 cites W2054150746 @default.
- W2922493357 cites W2068762252 @default.
- W2922493357 cites W2073383508 @default.
- W2922493357 cites W2084226339 @default.
- W2922493357 cites W2091378187 @default.
- W2922493357 cites W209407348 @default.
- W2922493357 cites W2097761831 @default.
- W2922493357 cites W2098085498 @default.
- W2922493357 cites W2099566069 @default.
- W2922493357 cites W2107277218 @default.
- W2922493357 cites W2118901699 @default.
- W2922493357 cites W2132013820 @default.
- W2922493357 cites W2132179935 @default.
- W2922493357 cites W2133370155 @default.
- W2922493357 cites W2140551998 @default.
- W2922493357 cites W2140614500 @default.
- W2922493357 cites W2154589460 @default.
- W2922493357 cites W2165948908 @default.
- W2922493357 cites W2192080449 @default.
- W2922493357 cites W2228221433 @default.
- W2922493357 cites W2409002231 @default.
- W2922493357 cites W2464584376 @default.
- W2922493357 cites W2480931704 @default.
- W2922493357 cites W254031714 @default.
- W2922493357 cites W2749424190 @default.
- W2922493357 cites W2771002949 @default.
- W2922493357 cites W4210961478 @default.
- W2922493357 doi "https://doi.org/10.3892/etm.2019.7370" @default.
- W2922493357 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6447801" @default.
- W2922493357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30988707" @default.
- W2922493357 hasPublicationYear "2019" @default.
- W2922493357 type Work @default.
- W2922493357 sameAs 2922493357 @default.
- W2922493357 citedByCount "12" @default.
- W2922493357 countsByYear W29224933572019 @default.
- W2922493357 countsByYear W29224933572020 @default.
- W2922493357 countsByYear W29224933572021 @default.
- W2922493357 countsByYear W29224933572022 @default.
- W2922493357 crossrefType "journal-article" @default.
- W2922493357 hasAuthorship W2922493357A5000214013 @default.
- W2922493357 hasAuthorship W2922493357A5005268649 @default.
- W2922493357 hasAuthorship W2922493357A5014942240 @default.
- W2922493357 hasAuthorship W2922493357A5018411567 @default.
- W2922493357 hasAuthorship W2922493357A5021889091 @default.
- W2922493357 hasAuthorship W2922493357A5034453700 @default.
- W2922493357 hasAuthorship W2922493357A5037995990 @default.
- W2922493357 hasAuthorship W2922493357A5041937683 @default.
- W2922493357 hasAuthorship W2922493357A5060165452 @default.
- W2922493357 hasAuthorship W2922493357A5080110690 @default.
- W2922493357 hasAuthorship W2922493357A5090818171 @default.
- W2922493357 hasBestOaLocation W29224933571 @default.
- W2922493357 hasConcept C121608353 @default.
- W2922493357 hasConcept C126322002 @default.
- W2922493357 hasConcept C142724271 @default.
- W2922493357 hasConcept C147447768 @default.
- W2922493357 hasConcept C1491633281 @default.
- W2922493357 hasConcept C203014093 @default.
- W2922493357 hasConcept C204232928 @default.
- W2922493357 hasConcept C2776256026 @default.
- W2922493357 hasConcept C2777714996 @default.
- W2922493357 hasConcept C2779013556 @default.
- W2922493357 hasConcept C2781018059 @default.
- W2922493357 hasConcept C2781182431 @default.
- W2922493357 hasConcept C29537977 @default.
- W2922493357 hasConcept C502942594 @default.
- W2922493357 hasConcept C54355233 @default.
- W2922493357 hasConcept C555283112 @default.
- W2922493357 hasConcept C71924100 @default.
- W2922493357 hasConcept C76419328 @default.
- W2922493357 hasConcept C81729549 @default.
- W2922493357 hasConcept C86492073 @default.
- W2922493357 hasConcept C86803240 @default.
- W2922493357 hasConceptScore W2922493357C121608353 @default.
- W2922493357 hasConceptScore W2922493357C126322002 @default.