FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2922518165> ?p ?o ?g. }

• W2922518165 endingPage "S487" @default.
• W2922518165 startingPage "S487" @default.
• W2922518165 abstract "Introduction: Hepatorenal Syndrome (HRS) is a serious complication in cirrhotic patients associated with high mortality and morbidity. The diagnosis of HRS has-evolved over the years, but is still limited due the complexity of patients who present with decompensated cirrhosis, and difficulty establishing the diagnosis in such patients. We aimed to assess the rate of HRS among hospitalized patients with cirrhosis and evaluated the diagnostic and treatment pattern in this high-risk population. Methods: A cross sectional chart review study of hospitalized patients with ICD diagnostic codes of liver cirrhosis and acute renal failure (ARF) from 2000-2016 was performed. 725 charts were reviewed. We excluded patients with a baseline creatinine of >1.5, without clinical or imaging evidence of ascites, and those with symptomatic heart failure or baseline ejection fraction less than 40%. 291 patients with decompensated liver cirrhosis and ascites were included in the analysis. Data was analyzed using SPSS® version 23. Descriptive statistics were applied. We used t test to compare continuous variables and chi square analysis for categorical variables. Data is presented as mean ± SEM (standard error of the mean). Results: Of the 291 patients included, mean age (years) = 55.7 ± 0.61, body mass index (kg/m2) =26.9±0.39. 65.5% were male. Baseline serum creatinine = 0.94 ± 0.14, first elevated creatinine = 2.28 ± 0.08, mean creatinine increase = 1.36 ± 0.08 mg/dl. 29.7% had a diagnosis of pre-renal azotemia, 25.1% had acute renal failure and 27.2% met the diagnostic criteria of HRS. 18.0% of the patients did not have a diagnosis pertinent to the elevation of serum creatinine. Intravenous fluid was administered to 92.3 % of patients with HRS and 75.4% received albumin within 48 hours of acute creatinine elevation. The combination of albumin/octreotide/midodrine was administered to 40%, and albumin/norepinephrine was given to 15.4% of HRS patients. In-hospital mortality rate was 14.1%, 23.3%, and 41.5% for patients with pre-renal azotemia, ARF and HRS respectively (p<0.01) Conclusion: HRS occurred in 27% of hospitalized patients with cirrhosis and acute kidney injury, and carried a high mortality risk despite a high rate of utilization of standard therapy. Further research is needed for rapid identification through specific biomarkers, timely intervention, and new more potent therapeutic modalities" @default.
• W2922518165 created "2019-03-22" @default.
• W2922518165 creator A5004348535 @default.
• W2922518165 creator A5022856730 @default.
• W2922518165 creator A5024754600 @default.
• W2922518165 creator A5027071032 @default.
• W2922518165 creator A5029815863 @default.
• W2922518165 creator A5033924096 @default.
• W2922518165 creator A5049335769 @default.
• W2922518165 creator A5059765784 @default.
• W2922518165 creator A5065420581 @default.
• W2922518165 creator A5068560032 @default.
• W2922518165 creator A5087503328 @default.
• W2922518165 date "2018-10-01" @default.
• W2922518165 modified "2023-09-23" @default.
• W2922518165 title "Management and Outcomes of Hepatorenal Syndrome at Urban Academic Medical Center: A Cross Sectional Study" @default.
• W2922518165 doi "https://doi.org/10.14309/00000434-201810001-00878" @default.
• W2922518165 hasPublicationYear "2018" @default.
• W2922518165 type Work @default.
• W2922518165 sameAs 2922518165 @default.
• W2922518165 citedByCount "0" @default.
• W2922518165 crossrefType "journal-article" @default.
• W2922518165 hasAuthorship W2922518165A5004348535 @default.
• W2922518165 hasAuthorship W2922518165A5022856730 @default.
• W2922518165 hasAuthorship W2922518165A5024754600 @default.
• W2922518165 hasAuthorship W2922518165A5027071032 @default.
• W2922518165 hasAuthorship W2922518165A5029815863 @default.
• W2922518165 hasAuthorship W2922518165A5033924096 @default.
• W2922518165 hasAuthorship W2922518165A5049335769 @default.
• W2922518165 hasAuthorship W2922518165A5059765784 @default.
• W2922518165 hasAuthorship W2922518165A5065420581 @default.
• W2922518165 hasAuthorship W2922518165A5068560032 @default.
• W2922518165 hasAuthorship W2922518165A5087503328 @default.
• W2922518165 hasConcept C126322002 @default.
• W2922518165 hasConcept C159641895 @default.
• W2922518165 hasConcept C2775919214 @default.
• W2922518165 hasConcept C2776988256 @default.
• W2922518165 hasConcept C2777214474 @default.
• W2922518165 hasConcept C2780306776 @default.
• W2922518165 hasConcept C2780496750 @default.
• W2922518165 hasConcept C2908647359 @default.
• W2922518165 hasConcept C71924100 @default.
• W2922518165 hasConcept C90924648 @default.
• W2922518165 hasConcept C99454951 @default.
• W2922518165 hasConceptScore W2922518165C126322002 @default.
• W2922518165 hasConceptScore W2922518165C159641895 @default.
• W2922518165 hasConceptScore W2922518165C2775919214 @default.
• W2922518165 hasConceptScore W2922518165C2776988256 @default.
• W2922518165 hasConceptScore W2922518165C2777214474 @default.
• W2922518165 hasConceptScore W2922518165C2780306776 @default.
• W2922518165 hasConceptScore W2922518165C2780496750 @default.
• W2922518165 hasConceptScore W2922518165C2908647359 @default.
• W2922518165 hasConceptScore W2922518165C71924100 @default.
• W2922518165 hasConceptScore W2922518165C90924648 @default.
• W2922518165 hasConceptScore W2922518165C99454951 @default.
• W2922518165 hasIssue "Supplement" @default.
• W2922518165 hasLocation W29225181651 @default.
• W2922518165 hasOpenAccess W2922518165 @default.
• W2922518165 hasPrimaryLocation W29225181651 @default.
• W2922518165 hasRelatedWork W1979079372 @default.
• W2922518165 hasRelatedWork W2110280698 @default.
• W2922518165 hasRelatedWork W2136034922 @default.
• W2922518165 hasRelatedWork W2207296767 @default.
• W2922518165 hasRelatedWork W2370022816 @default.
• W2922518165 hasRelatedWork W2464961298 @default.
• W2922518165 hasRelatedWork W2803936932 @default.
• W2922518165 hasRelatedWork W3201397909 @default.
• W2922518165 hasRelatedWork W4205141971 @default.
• W2922518165 hasRelatedWork W2922528030 @default.
• W2922518165 hasVolume "113" @default.
• W2922518165 isParatext "false" @default.
• W2922518165 isRetracted "false" @default.
• W2922518165 magId "2922518165" @default.
• W2922518165 workType "article" @default.