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- W29225610 abstract "Publisher Summary This chapter provides an overview of ecdysone workshops. The methods for the separation and analysis of ecdysteroids have undergone spectacular improvements, largely because of the introduction of high-performance liquid chromatography (HPLC) and the use of combined gas chromatography–mass spectrometry (GC–MS) of 1 H-NMR and 13 C-NMR. Ecdysone and/or 20-hydroxyecdysone are inactivated primarily by the esterification or epimerization of the C-3 hydroxyl group or, to a lesser extent, by the esterification of the C-2 hydroxyl group on the A nucleus. A relatively wide-spread inactivation pathway is the hydroxylation of the C-26 methyl group followed by oxidation to an ecdysonoic acid. In higher insect orders, like the dipterans, ovarian ecdysteroids play a role in the control of vitellogenin synthesis, whereas in other orders, they play a role in the early events of embryogenesis. Vitellogenic ovaries synthesize ecdysteroids at a given stage of their development; in some species, this synthesis occurs only towards the end of vitellogenin uptake; in others, it occurs at almost the same time as concomitantly the onset of vitellogenin synthesis." @default.
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- W29225610 date "1986-01-01" @default.
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- W29225610 title "INTRODUCTION: TEN YEARS OF ECDYSONE WORKSHOPS" @default.
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