FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2922969439> ?p ?o ?g. }

• W2922969439 abstract "Abstract Obtaining a comprehensive understanding of the gene regulatory networks, or gene cascades, involved in cell fate determination and cell lineage segregation in Caenorhabditis elegans is a long-standing challenge. Although RNA-sequencing (RNA-Seq) is a promising technique to resolve these questions, the bioinformatics tools to identify associated gene cascades from RNA-Seq data remain inadequate. To overcome these limitations, we developed Gene Cascade Finder (GCF) as a novel tool for building gene cascades by comparison of mutant and wild-type RNA-Seq data along with integrated information of protein-protein interactions, expression timing, and domains. Application of GCF to RNA-Seq data confirmed that SPN-4 and MEX-3 regulate the canonical Wnt pathway during embryonic development. Moreover, lin-35, hsp-3 , and gpa-12 were found to be involved in MEX-1-dependent neurogenesis, and MEX-3 was found to control the gene cascade promoting neurogenesis through lin-35 and apl-1 . Thus, GCF could be a useful tool for building gene cascades from RNA-Seq data." @default.
• W2922969439 created "2019-04-01" @default.
• W2922969439 creator A5014016931 @default.
• W2922969439 creator A5027846439 @default.
• W2922969439 creator A5039831856 @default.
• W2922969439 creator A5040006757 @default.
• W2922969439 creator A5042029425 @default.
• W2922969439 creator A5054983232 @default.
• W2922969439 creator A5058182120 @default.
• W2922969439 creator A5090024350 @default.
• W2922969439 date "2019-03-29" @default.
• W2922969439 modified "2023-09-27" @default.
• W2922969439 title "Gene Cascade Finder: A tool for identification of gene cascades and its application in<i>Caenorhabditis elegans</i>" @default.
• W2922969439 cites W1490161904 @default.
• W2922969439 cites W1542823905 @default.
• W2922969439 cites W1937572154 @default.
• W2922969439 cites W1967695632 @default.
• W2922969439 cites W1970466976 @default.
• W2922969439 cites W1981509058 @default.
• W2922969439 cites W1981742598 @default.
• W2922969439 cites W1989952069 @default.
• W2922969439 cites W2003261719 @default.
• W2922969439 cites W2006117889 @default.
• W2922969439 cites W2009993853 @default.
• W2922969439 cites W2015161609 @default.
• W2922969439 cites W2021977283 @default.
• W2922969439 cites W2022472106 @default.
• W2922969439 cites W2024103356 @default.
• W2922969439 cites W2030557396 @default.
• W2922969439 cites W2033200059 @default.
• W2922969439 cites W2043426556 @default.
• W2922969439 cites W2051649888 @default.
• W2922969439 cites W2072768871 @default.
• W2922969439 cites W2076205967 @default.
• W2922969439 cites W2081456504 @default.
• W2922969439 cites W2088894802 @default.
• W2922969439 cites W2093253451 @default.
• W2922969439 cites W2095289526 @default.
• W2922969439 cites W2096173332 @default.
• W2922969439 cites W2098581260 @default.
• W2922969439 cites W2100305481 @default.
• W2922969439 cites W2112443513 @default.
• W2922969439 cites W2113809075 @default.
• W2922969439 cites W2116928584 @default.
• W2922969439 cites W2122103373 @default.
• W2922969439 cites W2122798077 @default.
• W2922969439 cites W2123316581 @default.
• W2922969439 cites W2128491398 @default.
• W2922969439 cites W2129293106 @default.
• W2922969439 cites W2133871893 @default.
• W2922969439 cites W2136130231 @default.
• W2922969439 cites W2137351340 @default.
• W2922969439 cites W2137586531 @default.
• W2922969439 cites W2146138017 @default.
• W2922969439 cites W2154431984 @default.
• W2922969439 cites W2159675211 @default.
• W2922969439 cites W2162292349 @default.
• W2922969439 cites W2163485494 @default.
• W2922969439 cites W2410486665 @default.
• W2922969439 cites W2730417791 @default.
• W2922969439 cites W2766648070 @default.
• W2922969439 cites W4210323379 @default.
• W2922969439 cites W4230501579 @default.
• W2922969439 doi "https://doi.org/10.1101/593400" @default.
• W2922969439 hasPublicationYear "2019" @default.
• W2922969439 type Work @default.
• W2922969439 sameAs 2922969439 @default.
• W2922969439 citedByCount "0" @default.
• W2922969439 crossrefType "posted-content" @default.
• W2922969439 hasAuthorship W2922969439A5014016931 @default.
• W2922969439 hasAuthorship W2922969439A5027846439 @default.
• W2922969439 hasAuthorship W2922969439A5039831856 @default.
• W2922969439 hasAuthorship W2922969439A5040006757 @default.
• W2922969439 hasAuthorship W2922969439A5042029425 @default.
• W2922969439 hasAuthorship W2922969439A5054983232 @default.
• W2922969439 hasAuthorship W2922969439A5058182120 @default.
• W2922969439 hasAuthorship W2922969439A5090024350 @default.
• W2922969439 hasBestOaLocation W29229694391 @default.
• W2922969439 hasConcept C104317684 @default.
• W2922969439 hasConcept C107397762 @default.
• W2922969439 hasConcept C145103041 @default.
• W2922969439 hasConcept C150194340 @default.
• W2922969439 hasConcept C162317418 @default.
• W2922969439 hasConcept C163952510 @default.
• W2922969439 hasConcept C2778944004 @default.
• W2922969439 hasConcept C4746552 @default.
• W2922969439 hasConcept C54355233 @default.
• W2922969439 hasConcept C67705224 @default.
• W2922969439 hasConcept C70721500 @default.
• W2922969439 hasConcept C86339819 @default.
• W2922969439 hasConcept C86803240 @default.
• W2922969439 hasConceptScore W2922969439C104317684 @default.
• W2922969439 hasConceptScore W2922969439C107397762 @default.
• W2922969439 hasConceptScore W2922969439C145103041 @default.
• W2922969439 hasConceptScore W2922969439C150194340 @default.
• W2922969439 hasConceptScore W2922969439C162317418 @default.
• W2922969439 hasConceptScore W2922969439C163952510 @default.
• W2922969439 hasConceptScore W2922969439C2778944004 @default.
• W2922969439 hasConceptScore W2922969439C4746552 @default.
• W2922969439 hasConceptScore W2922969439C54355233 @default.

• next