FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2923078897> ?p ?o ?g. }

• W2923078897 endingPage "828" @default.
• W2923078897 startingPage "820" @default.
• W2923078897 abstract "Multi-walled carbon nanotubes (MWCNTs) have widespread use in industrial and consumer products and great potential in biomedical applications. This leads to inevitably their release into the environment and the formation of their toxic effects on organisms. These effects can change depending on their physicochemical characteristics. Therefore, the toxicological findings of MWCNTs are inconsistent. Their toxicities related to surface modification have not been elucidated in a holistic manner. Hence, this study was conducted to clarify their potential toxic effects on zebrafish embryos/larvae in a comprehensive approach using morphologic, biochemical and molecular parameters. Zebrafish embryos were exposed to 5, 10, 20 mg/L doses of MWCNTs-COOH at 4 h after fertilization and grown until 96 hpf. Physiological findings demonstrated that they induced a concentration-dependent increase in the mortality rate, delayed hatching and decrease in the heartbeat rate. Moreover, it caused abnormalities including yolk sac edema, pericardial edema, head, tail malformations, and vertebral deformities. These effects may be due to the alterations in antioxidant and immune system related gene expressions after their entry into zebrafish embryo/larvae. The entry was confirmed from the evaluation of Raman spectra collected from the head, yolk sac, and tail of control and the nanotube treated groups. The gene expression analysis indicated the changes in the expression of oxidative stress (mtf-1, hsp70, and nfkb) and innate immune system (il-1β, tlr-4, tlr-22, trf, and cebp) related genes, especially an increased in the expression of the hsp70 and il-1β. These findings proved the developmental toxicities of MWCNTs-COOH on the zebrafish embryos/larvae." @default.
• W2923078897 created "2019-04-01" @default.
• W2923078897 creator A5037825018 @default.
• W2923078897 creator A5089816252 @default.
• W2923078897 creator A5091770685 @default.
• W2923078897 date "2019-06-01" @default.
• W2923078897 modified "2023-10-06" @default.
• W2923078897 title "A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae" @default.
• W2923078897 cites W1613816262 @default.
• W2923078897 cites W1615535881 @default.
• W2923078897 cites W1751362639 @default.
• W2923078897 cites W1964725940 @default.
• W2923078897 cites W1965508264 @default.
• W2923078897 cites W1967133409 @default.
• W2923078897 cites W1970479761 @default.
• W2923078897 cites W1984095783 @default.
• W2923078897 cites W1984411147 @default.
• W2923078897 cites W1986492157 @default.
• W2923078897 cites W1989522556 @default.
• W2923078897 cites W1998656352 @default.
• W2923078897 cites W2000071229 @default.
• W2923078897 cites W2005716425 @default.
• W2923078897 cites W2006136808 @default.
• W2923078897 cites W2022964976 @default.
• W2923078897 cites W2034343019 @default.
• W2923078897 cites W2040101447 @default.
• W2923078897 cites W2043933297 @default.
• W2923078897 cites W2056477000 @default.
• W2923078897 cites W2060715824 @default.
• W2923078897 cites W2061047871 @default.
• W2923078897 cites W2062663211 @default.
• W2923078897 cites W2064187058 @default.
• W2923078897 cites W2071052983 @default.
• W2923078897 cites W2085733813 @default.
• W2923078897 cites W2090903178 @default.
• W2923078897 cites W2101183319 @default.
• W2923078897 cites W2102864326 @default.
• W2923078897 cites W2105922265 @default.
• W2923078897 cites W2112844455 @default.
• W2923078897 cites W2115471288 @default.
• W2923078897 cites W2131781547 @default.
• W2923078897 cites W2135221921 @default.
• W2923078897 cites W2138573825 @default.
• W2923078897 cites W2149506727 @default.
• W2923078897 cites W2152920690 @default.
• W2923078897 cites W2156661377 @default.
• W2923078897 cites W2168076509 @default.
• W2923078897 cites W2178188685 @default.
• W2923078897 cites W2254623713 @default.
• W2923078897 cites W2268976488 @default.
• W2923078897 cites W2287982871 @default.
• W2923078897 cites W2312342716 @default.
• W2923078897 cites W2312422565 @default.
• W2923078897 cites W2321508118 @default.
• W2923078897 cites W2321918425 @default.
• W2923078897 cites W2341249542 @default.
• W2923078897 cites W2342873971 @default.
• W2923078897 cites W2433022886 @default.
• W2923078897 cites W2463078259 @default.
• W2923078897 cites W2465435050 @default.
• W2923078897 cites W2605134034 @default.
• W2923078897 cites W2758320018 @default.
• W2923078897 cites W2766271717 @default.
• W2923078897 cites W2766930262 @default.
• W2923078897 cites W2789772598 @default.
• W2923078897 cites W2792612653 @default.
• W2923078897 cites W2795132421 @default.
• W2923078897 cites W753830904 @default.
• W2923078897 doi "https://doi.org/10.1016/j.chemosphere.2019.03.083" @default.
• W2923078897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30904762" @default.
• W2923078897 hasPublicationYear "2019" @default.
• W2923078897 type Work @default.
• W2923078897 sameAs 2923078897 @default.
• W2923078897 citedByCount "20" @default.
• W2923078897 countsByYear W29230788972019 @default.
• W2923078897 countsByYear W29230788972020 @default.
• W2923078897 countsByYear W29230788972021 @default.
• W2923078897 countsByYear W29230788972022 @default.
• W2923078897 countsByYear W29230788972023 @default.
• W2923078897 crossrefType "journal-article" @default.
• W2923078897 hasAuthorship W2923078897A5037825018 @default.
• W2923078897 hasAuthorship W2923078897A5089816252 @default.
• W2923078897 hasAuthorship W2923078897A5091770685 @default.
• W2923078897 hasConcept C104317684 @default.
• W2923078897 hasConcept C12554922 @default.
• W2923078897 hasConcept C136449434 @default.
• W2923078897 hasConcept C16685009 @default.
• W2923078897 hasConcept C171250308 @default.
• W2923078897 hasConcept C172680121 @default.
• W2923078897 hasConcept C179335377 @default.
• W2923078897 hasConcept C185592680 @default.
• W2923078897 hasConcept C192562407 @default.
• W2923078897 hasConcept C196843134 @default.
• W2923078897 hasConcept C203014093 @default.
• W2923078897 hasConcept C2776151105 @default.
• W2923078897 hasConcept C2776878037 @default.
• W2923078897 hasConcept C2777043721 @default.
• W2923078897 hasConcept C2778004101 @default.

• next