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• W2923213360 endingPage "602" @default.
• W2923213360 startingPage "597" @default.
• W2923213360 abstract "Crop breeding aims to generate pure inbred lines with multiple desired traits. Doubled haploid (DH) and genome editing using CRISPR/Cas9 are two powerful game-changing technologies in crop breeding. However, both of them still fall short for rapid generation of pure elite lines with integrated favorable traits. Here, we report the development of a Haploid-Inducer Mediated Genome Editing (IMGE) approach, which utilizes a maize haploid inducer line carrying a CRISPR/Cas9 cassette targeting for a desired agronomic trait to pollinate an elite maize inbred line and to generate genome-edited haploids in the elite maize background. Homozygous pure DH lines with the desired trait improvement could be generated within two generations, thus bypassing the lengthy procedure of repeated crossing and backcrossing used in conventional breeding for integrating a desirable trait into elite commercial backgrounds." @default.
• W2923213360 created "2019-04-01" @default.
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• W2923213360 date "2019-04-01" @default.
• W2923213360 modified "2023-10-16" @default.
• W2923213360 title "Development of a Haploid-Inducer Mediated Genome Editing System for Accelerating Maize Breeding" @default.
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• W2923213360 doi "https://doi.org/10.1016/j.molp.2019.03.006" @default.
• W2923213360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30902686" @default.
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