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- W2923214423 abstract "Insulin signaling is a conserved pathway in all metazoans. This pathway contributed toward primordial metazoans responding to a greater diversity of environmental signals by modulating nutritional storage, reproduction, and longevity. Most of our knowledge of insulin signaling in insects comes from the vinegar fly, Drosophila melanogaster, where it has been extensively studied and shown to control several physiological processes. Mosquitoes are the most important vectors of human disease in the world and their control constitutes a significant area of research. Recent studies have shown the importance of insulin signaling in multiple physiological processes such as reproduction, innate immunity, lifespan, and vectorial capacity in mosquitoes. Although insulin-like peptides have been identified and functionally characterized from many mosquito species, a comprehensive review of this pathway in mosquitoes is needed. To fill this gap, our review provides up-to-date knowledge of this subfield." @default.
- W2923214423 created "2019-04-01" @default.
- W2923214423 creator A5021295755 @default.
- W2923214423 creator A5026473563 @default.
- W2923214423 creator A5056598388 @default.
- W2923214423 date "2019-03-22" @default.
- W2923214423 modified "2023-10-11" @default.
- W2923214423 title "Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead" @default.
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- W2923214423 doi "https://doi.org/10.3389/fendo.2019.00166" @default.
- W2923214423 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6448002" @default.
- W2923214423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30984106" @default.
- W2923214423 hasPublicationYear "2019" @default.
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