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• W2923344487 abstract "Three-dimensional (3D) single-particle tracking (SPT) is a key tool for studying dynamic processes in the life sciences. However, conventional optical elements utilizing light fields impose an inherent trade-off between lateral and axial resolution, preventing SPT with high spatiotemporal resolution across an extended volume. We overcome the typical loss in spatial resolution that accompanies light-field-based approaches to obtain 3D information by placing a standard microscope coverslip patterned with a multifunctional, light-field metasurface on a specimen. This approach enables an otherwise unmodified microscope to gather 3D information at an enhanced spatial resolution. We demonstrate simultaneous tracking of multiple fluorescent particles within a large 0.5 × 0.5 × 0.3 mm3 volume using a standard epi-fluorescent microscope with submicron lateral and micron-level axial resolution." @default.
• W2923344487 created "2019-04-01" @default.
• W2923344487 creator A5014044649 @default.
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• W2923344487 date "2019-03-22" @default.
• W2923344487 modified "2023-10-17" @default.
• W2923344487 title "A Light-Field Metasurface for High-Resolution Single-Particle Tracking" @default.
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• W2923344487 doi "https://doi.org/10.1021/acs.nanolett.8b04673" @default.
• W2923344487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30897902" @default.
• W2923344487 hasPublicationYear "2019" @default.
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