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- W2923494148 abstract "Fibrosis plays a fundamental role in the initiation and maintenance of AF, mainly due to enhanced automaticity and anisotropy-related re-entry. The identification and quantification of atrial fibrosis is achieved either preprocedurally by late gadolinium enhancement MRI or intraprocedurally using electroanatomic voltage mapping. The presence and extent of left atrial fibrosis among AF patients may influence relevant decision making regarding the need for anticoagulation, the adoption of rate versus rhythm control and mainly the type of ablation strategy that will be followed during interventional treatment. Several types of individualised substrate modifications targeting atrial fibrotic areas have been proposed, although their impact on patient outcome needs to be further investigated in adequately powered prospective randomised controlled clinical trials." @default.
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- W2923494148 date "2019-03-12" @default.
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- W2923494148 title "Atrial Fibrosis: Translational Considerations for the Management of AF Patients" @default.
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- W2923494148 doi "https://doi.org/10.15420/aer.2018.79.3" @default.
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