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- W2923536163 endingPage "366" @default.
- W2923536163 startingPage "358" @default.
- W2923536163 abstract "The intermediates operating in the cytochrome P450 catalytic cycle have been investigated for more than half a century, fascinating many enzymologists. Each intermediate has its unique role to carry out diverse oxidations. Natural time course of the catalytic cycle is quite fast, hence, not all of the reactive intermediates could be isolated during physiological catalysis. Different high-valent iron intermediates have been proposed as primary oxidants: the candidates are compound 0 (Cpd 0, [FeOOH][Formula: see text]P450) and compound I (Cpd I, Fe(IV)[Formula: see text]O por[Formula: see text]P450). Among them, the role of Cpd I in hydroxylation is fairly well understood due the discovery of the peroxide shunt. This review endeavors to put the outstanding research efforts conducted to isolate and characterize the intermediates together. In addition to spectral features of each intermediate in the catalytic cycle, the oxidizing powers of Cpd 0 and Cpd I will be discussed along with most recent scientific findings." @default.
- W2923536163 created "2019-04-01" @default.
- W2923536163 creator A5083576479 @default.
- W2923536163 date "2019-04-01" @default.
- W2923536163 modified "2023-09-26" @default.
- W2923536163 title "One small step for cytochrome P450 in its catalytic cycle, one giant leap for enzymology" @default.
- W2923536163 cites W1485357293 @default.
- W2923536163 cites W1492141962 @default.
- W2923536163 cites W1498584605 @default.
- W2923536163 cites W1518095282 @default.
- W2923536163 cites W1532212858 @default.
- W2923536163 cites W1539518310 @default.
- W2923536163 cites W1547482025 @default.
- W2923536163 cites W1581865960 @default.
- W2923536163 cites W1589214741 @default.
- W2923536163 cites W1710186203 @default.
- W2923536163 cites W1757808457 @default.
- W2923536163 cites W1827138247 @default.
- W2923536163 cites W1880099783 @default.
- W2923536163 cites W1963868844 @default.
- W2923536163 cites W1965637904 @default.
- W2923536163 cites W1967211277 @default.
- W2923536163 cites W1967602904 @default.
- W2923536163 cites W1968400590 @default.
- W2923536163 cites W1970915662 @default.
- W2923536163 cites W1972864845 @default.
- W2923536163 cites W1972905772 @default.
- W2923536163 cites W1974190853 @default.
- W2923536163 cites W1974553522 @default.
- W2923536163 cites W1975262546 @default.
- W2923536163 cites W1976312818 @default.
- W2923536163 cites W1977396869 @default.
- W2923536163 cites W1979354700 @default.
- W2923536163 cites W1983708374 @default.
- W2923536163 cites W1984464701 @default.
- W2923536163 cites W1985856334 @default.
- W2923536163 cites W1987575621 @default.
- W2923536163 cites W1987588083 @default.
- W2923536163 cites W1987856692 @default.
- W2923536163 cites W1989744091 @default.
- W2923536163 cites W199420752 @default.
- W2923536163 cites W1994646181 @default.
- W2923536163 cites W2000270075 @default.
- W2923536163 cites W2001406413 @default.
- W2923536163 cites W2002012155 @default.
- W2923536163 cites W2002497805 @default.
- W2923536163 cites W2003092651 @default.
- W2923536163 cites W2003105919 @default.
- W2923536163 cites W2004552374 @default.
- W2923536163 cites W2005145448 @default.
- W2923536163 cites W2009732646 @default.
- W2923536163 cites W2010800891 @default.
- W2923536163 cites W2012134616 @default.
- W2923536163 cites W2018292851 @default.
- W2923536163 cites W2021406372 @default.
- W2923536163 cites W2024908060 @default.
- W2923536163 cites W2025973496 @default.
- W2923536163 cites W2026696526 @default.
- W2923536163 cites W2030657372 @default.
- W2923536163 cites W2032087185 @default.
- W2923536163 cites W2032090992 @default.
- W2923536163 cites W2032941773 @default.
- W2923536163 cites W2034834397 @default.
- W2923536163 cites W2034936033 @default.
- W2923536163 cites W2037362938 @default.
- W2923536163 cites W2039485473 @default.
- W2923536163 cites W2039907315 @default.
- W2923536163 cites W2042939317 @default.
- W2923536163 cites W2042963112 @default.
- W2923536163 cites W2047034176 @default.
- W2923536163 cites W2047560453 @default.
- W2923536163 cites W2049865119 @default.
- W2923536163 cites W2051850235 @default.
- W2923536163 cites W2055820030 @default.
- W2923536163 cites W2059045499 @default.
- W2923536163 cites W2059095560 @default.
- W2923536163 cites W2059247990 @default.
- W2923536163 cites W2060180669 @default.
- W2923536163 cites W2060551415 @default.
- W2923536163 cites W2061370608 @default.
- W2923536163 cites W2061547898 @default.
- W2923536163 cites W2065895273 @default.
- W2923536163 cites W2066345974 @default.
- W2923536163 cites W2067504663 @default.
- W2923536163 cites W2068297474 @default.
- W2923536163 cites W2068925710 @default.
- W2923536163 cites W2077621515 @default.
- W2923536163 cites W2079199633 @default.
- W2923536163 cites W2083592891 @default.
- W2923536163 cites W2085585038 @default.
- W2923536163 cites W2086375922 @default.
- W2923536163 cites W2090991101 @default.
- W2923536163 cites W2091087315 @default.
- W2923536163 cites W2091840451 @default.
- W2923536163 cites W2093905655 @default.
- W2923536163 cites W2094293924 @default.
- W2923536163 cites W2095873332 @default.
- W2923536163 cites W2102776090 @default.