Matches in SemOpenAlex for { <https://semopenalex.org/work/W2923713426> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2923713426 abstract "Abstract The polygenic risk score for schizophrenia (SZ-PRS) is associated with creativity and psychiatric disorders, including cannabis use. We have investigated the selection pressures on sequence variants that predispose to schizophrenia in the Icelandic population and find no evidence of selective advantage of a high SZ-PRS. Rare copy-number variants conferring moderate to high risk of psychiatric illness are, however, associated with having fewer children and are under negative selection. We also examined the correlation between SZ-PRS and the number of relationships producing offspring in 81,713 adult Icelanders without diagnosis of schizophrenia. SZ-PRS is associated with increased likelihood of having offspring with more than one mate (P = 7.9 x 10-12). Thus, while common variants that increase schizophrenia risk may not be under strong selection they influence mating behaviour in adults who do not have the disorder." @default.
- W2923713426 created "2019-04-01" @default.
- W2923713426 creator A5008553103 @default.
- W2923713426 creator A5009208804 @default.
- W2923713426 creator A5018239255 @default.
- W2923713426 creator A5018986259 @default.
- W2923713426 creator A5042302428 @default.
- W2923713426 creator A5084745044 @default.
- W2923713426 creator A5087161248 @default.
- W2923713426 date "2019-01-01" @default.
- W2923713426 modified "2023-09-26" @default.
- W2923713426 title "Effect of Schizophrenia Risk Variants On Mating and Fecundity" @default.
- W2923713426 doi "https://doi.org/10.1016/j.euroneuro.2017.06.104" @default.
- W2923713426 hasPublicationYear "2019" @default.
- W2923713426 type Work @default.
- W2923713426 sameAs 2923713426 @default.
- W2923713426 citedByCount "0" @default.
- W2923713426 crossrefType "journal-article" @default.
- W2923713426 hasAuthorship W2923713426A5008553103 @default.
- W2923713426 hasAuthorship W2923713426A5009208804 @default.
- W2923713426 hasAuthorship W2923713426A5018239255 @default.
- W2923713426 hasAuthorship W2923713426A5018986259 @default.
- W2923713426 hasAuthorship W2923713426A5042302428 @default.
- W2923713426 hasAuthorship W2923713426A5084745044 @default.
- W2923713426 hasAuthorship W2923713426A5087161248 @default.
- W2923713426 hasConcept C104317684 @default.
- W2923713426 hasConcept C112672928 @default.
- W2923713426 hasConcept C118552586 @default.
- W2923713426 hasConcept C135763542 @default.
- W2923713426 hasConcept C153209595 @default.
- W2923713426 hasConcept C154945302 @default.
- W2923713426 hasConcept C15744967 @default.
- W2923713426 hasConcept C2776412080 @default.
- W2923713426 hasConcept C2779234561 @default.
- W2923713426 hasConcept C2908647359 @default.
- W2923713426 hasConcept C2993137441 @default.
- W2923713426 hasConcept C41008148 @default.
- W2923713426 hasConcept C514575182 @default.
- W2923713426 hasConcept C54355233 @default.
- W2923713426 hasConcept C67283656 @default.
- W2923713426 hasConcept C71924100 @default.
- W2923713426 hasConcept C81917197 @default.
- W2923713426 hasConcept C86803240 @default.
- W2923713426 hasConcept C99454951 @default.
- W2923713426 hasConceptScore W2923713426C104317684 @default.
- W2923713426 hasConceptScore W2923713426C112672928 @default.
- W2923713426 hasConceptScore W2923713426C118552586 @default.
- W2923713426 hasConceptScore W2923713426C135763542 @default.
- W2923713426 hasConceptScore W2923713426C153209595 @default.
- W2923713426 hasConceptScore W2923713426C154945302 @default.
- W2923713426 hasConceptScore W2923713426C15744967 @default.
- W2923713426 hasConceptScore W2923713426C2776412080 @default.
- W2923713426 hasConceptScore W2923713426C2779234561 @default.
- W2923713426 hasConceptScore W2923713426C2908647359 @default.
- W2923713426 hasConceptScore W2923713426C2993137441 @default.
- W2923713426 hasConceptScore W2923713426C41008148 @default.
- W2923713426 hasConceptScore W2923713426C514575182 @default.
- W2923713426 hasConceptScore W2923713426C54355233 @default.
- W2923713426 hasConceptScore W2923713426C67283656 @default.
- W2923713426 hasConceptScore W2923713426C71924100 @default.
- W2923713426 hasConceptScore W2923713426C81917197 @default.
- W2923713426 hasConceptScore W2923713426C86803240 @default.
- W2923713426 hasConceptScore W2923713426C99454951 @default.
- W2923713426 hasLocation W29237134261 @default.
- W2923713426 hasOpenAccess W2923713426 @default.
- W2923713426 hasPrimaryLocation W29237134261 @default.
- W2923713426 hasRelatedWork W1541766870 @default.
- W2923713426 hasRelatedWork W1989054333 @default.
- W2923713426 hasRelatedWork W2006311894 @default.
- W2923713426 hasRelatedWork W2171782525 @default.
- W2923713426 hasRelatedWork W2178083212 @default.
- W2923713426 hasRelatedWork W2313318538 @default.
- W2923713426 hasRelatedWork W2923713426 @default.
- W2923713426 hasRelatedWork W2959357444 @default.
- W2923713426 hasRelatedWork W4205327433 @default.
- W2923713426 hasRelatedWork W4255370743 @default.
- W2923713426 isParatext "false" @default.
- W2923713426 isRetracted "false" @default.
- W2923713426 magId "2923713426" @default.
- W2923713426 workType "article" @default.