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- W2924103383 abstract "Abstract Background H19 polymorphisms have been reported to correlate with an increased susceptibility to a few types of cancers, although their role in neuroblastoma has not yet been clarified. Materials and methods We investigated the association between three single polymorphisms (rs2839698 G>A, rs3024270 C>G, and rs217727 G>A) and neuroblastoma susceptibility in Chinese Han populations. Three hundred ninety-three neuroblastoma patients and 812 healthy controls were enrolled from the Henan and Guangdong provinces. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to determine the strength of the association of interest. Results Separated and combined analyses revealed no associations of the rs2839698 G>A, rs3024270 C>G or rs217727 G>A polymorphisms and neuroblastoma susceptibility. In the stratification analysis, female children with rs3024270 GG genotypes had an increased neuroblastoma risk (adjusted OR = 1.61, 95% CI = 1.04–2.50, P=0.032). Conclusion The rs3024270 GG genotype might contribute to an increased neuroblastoma susceptibility in female Chinese children." @default.
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- W2924103383 date "2019-04-01" @default.
- W2924103383 modified "2023-10-03" @default.
- W2924103383 title "Associations between <i>H19</i> polymorphisms and neuroblastoma risk in Chinese children" @default.
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- W2924103383 doi "https://doi.org/10.1042/bsr20181582" @default.
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