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• W2924384121 abstract "A simple count of the PAINReportIt® number of neuropathic descriptors (PR-NNP) was only moderately correlated with two other valid neuropathic pain measures. The study aim was to develop a new PR-NNP score that maximizes the accuracy of classifying known groups of patients with sickle cell disease (SCD) who had sensitization or normal sensation and evaluate its associations with scores on the self-report version of the Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and the Neuropathic Pain Symptom Inventory (NPSI). In a cross-sectional, single-session, exploratory study of existing data, 180 adults of African ancestry with SCD completed PAINReportIt® (a computerized version of the McGill Pain Questionnaire), thermal and mechanical quantitative sensory testing (Medoc TSA II), S-LANSS, and NPSI from April 2015 to August 2017. Among the participants, most were female (59%), and ranging in age between 19 to 66 years (mean = 36.5±11.4). Using the number word count to score the PR-NNP sensitivity was 21% and specificity was 89%. We developed a weighted score for the PR-NNP and evaluated its sensitivity and specificity to sensitization or normal sensation groups. We computed weights for the sensory pain quality descriptors using the logarithms of odds ratios as weights. The logarithms of odds ratio provided a score for the PR-NNP with sensitivity=81% and specificity=60%, which was better than the S-LANSS’ sensitivity=44% and specificity=60% and the NPSI's sensitivity=52% and specificity=71%. Our new score offers a pain screening tool to discriminate between groups with sensitization or normal sensation, which is important for healthcare provider decision making for prescription of analgesics and treatment goals. Future research is recommended to strengthen the value of the PR-NNP for discrimination of pain type by inclusion of other dimensions of pain such as pain intensity. Supported by grant number R01HL124945. A simple count of the PAINReportIt® number of neuropathic descriptors (PR-NNP) was only moderately correlated with two other valid neuropathic pain measures. The study aim was to develop a new PR-NNP score that maximizes the accuracy of classifying known groups of patients with sickle cell disease (SCD) who had sensitization or normal sensation and evaluate its associations with scores on the self-report version of the Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and the Neuropathic Pain Symptom Inventory (NPSI). In a cross-sectional, single-session, exploratory study of existing data, 180 adults of African ancestry with SCD completed PAINReportIt® (a computerized version of the McGill Pain Questionnaire), thermal and mechanical quantitative sensory testing (Medoc TSA II), S-LANSS, and NPSI from April 2015 to August 2017. Among the participants, most were female (59%), and ranging in age between 19 to 66 years (mean = 36.5±11.4). Using the number word count to score the PR-NNP sensitivity was 21% and specificity was 89%. We developed a weighted score for the PR-NNP and evaluated its sensitivity and specificity to sensitization or normal sensation groups. We computed weights for the sensory pain quality descriptors using the logarithms of odds ratios as weights. The logarithms of odds ratio provided a score for the PR-NNP with sensitivity=81% and specificity=60%, which was better than the S-LANSS’ sensitivity=44% and specificity=60% and the NPSI's sensitivity=52% and specificity=71%. Our new score offers a pain screening tool to discriminate between groups with sensitization or normal sensation, which is important for healthcare provider decision making for prescription of analgesics and treatment goals. Future research is recommended to strengthen the value of the PR-NNP for discrimination of pain type by inclusion of other dimensions of pain such as pain intensity. Supported by grant number R01HL124945." @default.
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• W2924384121 date "2019-04-01" @default.
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• W2924384121 title "(176) New Scoring for Pain Quality Descriptors: Associations with Quantitative Sensory Testing in Adults with Sickle Cell Disease" @default.
• W2924384121 doi "https://doi.org/10.1016/j.jpain.2019.01.096" @default.
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