Matches in SemOpenAlex for { <https://semopenalex.org/work/W2924639078> ?p ?o ?g. }
- W2924639078 abstract "Adipocytic tumors are rare in children and are mostly benign. Less than 25 cases of pediatric well-differentiated liposarcoma (WDLPS), atypical lipomatous tumors (ALT), and dedifferentiated liposarcoma (DDLPS) have been reported. Among them, only three cases were genetically analyzed. We describe the genetic features of a rapidly growing adipose tumor that occurred in the thigh of a 7-year-old girl. Histologically, it was composed of mature adipocytic cells with a few atypia. Molecular analysis showed high-level amplification of the 12q13-21 region including MDM2 among 64 amplified genes. MDM2 amplification is a diagnostic hallmark of ALT/WDLPS/DDLPS. In adult cases, it is typically located in ring or giant marker chromosomes. In the present case, extra-copies of MDM2 were located on double minute chromosomes (dmin). This raised the hypothesis of dmin being precursors of adult's rings and giant markers and may provide indications for a better understanding of the mechanisms of adipose tumor oncogenesis." @default.
- W2924639078 created "2019-04-01" @default.
- W2924639078 creator A5024150695 @default.
- W2924639078 creator A5058696789 @default.
- W2924639078 creator A5067940829 @default.
- W2924639078 creator A5074951570 @default.
- W2924639078 creator A5078415573 @default.
- W2924639078 creator A5083225766 @default.
- W2924639078 creator A5087388679 @default.
- W2924639078 creator A5087907084 @default.
- W2924639078 date "2019-04-13" @default.
- W2924639078 modified "2023-10-18" @default.
- W2924639078 title "Double minute chromosomes harboring <i>MDM2</i> amplification in a pediatric atypical lipomatous tumor" @default.
- W2924639078 cites W1509645770 @default.
- W2924639078 cites W1556753125 @default.
- W2924639078 cites W1576330810 @default.
- W2924639078 cites W1791597392 @default.
- W2924639078 cites W1919521860 @default.
- W2924639078 cites W1966718737 @default.
- W2924639078 cites W1967299474 @default.
- W2924639078 cites W1976650375 @default.
- W2924639078 cites W1986820103 @default.
- W2924639078 cites W2000486530 @default.
- W2924639078 cites W2000740779 @default.
- W2924639078 cites W2011273926 @default.
- W2924639078 cites W2015236057 @default.
- W2924639078 cites W2020439568 @default.
- W2924639078 cites W2023152232 @default.
- W2924639078 cites W2031435644 @default.
- W2924639078 cites W2034292565 @default.
- W2924639078 cites W2034715071 @default.
- W2924639078 cites W2045765958 @default.
- W2924639078 cites W2055214124 @default.
- W2924639078 cites W2061336075 @default.
- W2924639078 cites W2069228338 @default.
- W2924639078 cites W2072066791 @default.
- W2924639078 cites W2087409550 @default.
- W2924639078 cites W2097920585 @default.
- W2924639078 cites W2109948920 @default.
- W2924639078 cites W2118309445 @default.
- W2924639078 cites W2208513108 @default.
- W2924639078 cites W2587686129 @default.
- W2924639078 cites W2715703910 @default.
- W2924639078 cites W2735745686 @default.
- W2924639078 doi "https://doi.org/10.1002/gcc.22754" @default.
- W2924639078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30887579" @default.
- W2924639078 hasPublicationYear "2019" @default.
- W2924639078 type Work @default.
- W2924639078 sameAs 2924639078 @default.
- W2924639078 citedByCount "4" @default.
- W2924639078 countsByYear W29246390782021 @default.
- W2924639078 countsByYear W29246390782022 @default.
- W2924639078 crossrefType "journal-article" @default.
- W2924639078 hasAuthorship W2924639078A5024150695 @default.
- W2924639078 hasAuthorship W2924639078A5058696789 @default.
- W2924639078 hasAuthorship W2924639078A5067940829 @default.
- W2924639078 hasAuthorship W2924639078A5074951570 @default.
- W2924639078 hasAuthorship W2924639078A5078415573 @default.
- W2924639078 hasAuthorship W2924639078A5083225766 @default.
- W2924639078 hasAuthorship W2924639078A5087388679 @default.
- W2924639078 hasAuthorship W2924639078A5087907084 @default.
- W2924639078 hasBestOaLocation W29246390782 @default.
- W2924639078 hasConcept C104317684 @default.
- W2924639078 hasConcept C134018914 @default.
- W2924639078 hasConcept C142724271 @default.
- W2924639078 hasConcept C171089720 @default.
- W2924639078 hasConcept C204232928 @default.
- W2924639078 hasConcept C2776192174 @default.
- W2924639078 hasConcept C2778256501 @default.
- W2924639078 hasConcept C2779568860 @default.
- W2924639078 hasConcept C2781034694 @default.
- W2924639078 hasConcept C2781225692 @default.
- W2924639078 hasConcept C2781283455 @default.
- W2924639078 hasConcept C2781289014 @default.
- W2924639078 hasConcept C30481170 @default.
- W2924639078 hasConcept C502942594 @default.
- W2924639078 hasConcept C53226629 @default.
- W2924639078 hasConcept C54355233 @default.
- W2924639078 hasConcept C555283112 @default.
- W2924639078 hasConcept C71924100 @default.
- W2924639078 hasConcept C7602840 @default.
- W2924639078 hasConcept C86803240 @default.
- W2924639078 hasConceptScore W2924639078C104317684 @default.
- W2924639078 hasConceptScore W2924639078C134018914 @default.
- W2924639078 hasConceptScore W2924639078C142724271 @default.
- W2924639078 hasConceptScore W2924639078C171089720 @default.
- W2924639078 hasConceptScore W2924639078C204232928 @default.
- W2924639078 hasConceptScore W2924639078C2776192174 @default.
- W2924639078 hasConceptScore W2924639078C2778256501 @default.
- W2924639078 hasConceptScore W2924639078C2779568860 @default.
- W2924639078 hasConceptScore W2924639078C2781034694 @default.
- W2924639078 hasConceptScore W2924639078C2781225692 @default.
- W2924639078 hasConceptScore W2924639078C2781283455 @default.
- W2924639078 hasConceptScore W2924639078C2781289014 @default.
- W2924639078 hasConceptScore W2924639078C30481170 @default.
- W2924639078 hasConceptScore W2924639078C502942594 @default.
- W2924639078 hasConceptScore W2924639078C53226629 @default.
- W2924639078 hasConceptScore W2924639078C54355233 @default.
- W2924639078 hasConceptScore W2924639078C555283112 @default.
- W2924639078 hasConceptScore W2924639078C71924100 @default.