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- W292489613 abstract "Publisher Summary The popularity of continuous cell lines lies in their convenience as the sources of pure populations of macrophages and in the great range of macrophage-specific properties manifested. The cell lines can be easily maintained by laboratory personnel familiar with tissue culture methods. The cell lines are unique for biochemical, immunological, development, and regulation studies in which the absence of other cell types is essential. The continuous growth of the cell lines allows the selection of variants with altered macrophage properties for physiological studies during different stages of the cell cycle. The lines have variable amounts of ectoenzymes and adenosine deaminase reported to be correlated with macrophage maturation or activation and display macrophage-specific antigen recognized by a hybridoma antibody and an antigen present only on activated macrophages. Some lines, such as WEHI-3, show no activity for a number of assays and targets tested. Spontaneous cytotoxicity in apparent absence of activating agents is manifested by several lines against some T and B lymphoid tumors, myeloblast leukemia, and transformed fibroblasts." @default.
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- W292489613 date "1981-01-01" @default.
- W292489613 modified "2023-09-25" @default.
- W292489613 title "CONTINUOUS CELL LINES WITH PROPERTIES OF MONONUCLEAR PHAGOCYTES" @default.
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- W292489613 doi "https://doi.org/10.1016/b978-0-12-044220-1.50023-4" @default.
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