Matches in SemOpenAlex for { <https://semopenalex.org/work/W2925475067> ?p ?o ?g. }
- W2925475067 endingPage "e626" @default.
- W2925475067 startingPage "e618" @default.
- W2925475067 abstract "Chemotherapy is no longer the only viable option for patients with locally advanced or metastatic urothelial carcinoma. Immunotherapy, as checkpoint inhibition, has received United States Food and Drug Administration approval in the preceding several years, both in the second-line and first-line for cisplatin-ineligible patients. Those who respond often do so durably; however, response rates in the first line are 23% to 24%, and are lower in the second line. With a focus on urothelial carcinoma, this review discusses the tumor microenvironment and its negative influence on anti-tumor immunity, as well as measures to counteract immune suppression or evasion. The review then describes a range of current clinical trials implementing these measures in the form of programmed death-combination therapy, specifically in advanced bladder and urothelial cancers." @default.
- W2925475067 created "2019-04-11" @default.
- W2925475067 creator A5071418777 @default.
- W2925475067 creator A5074207420 @default.
- W2925475067 date "2019-06-01" @default.
- W2925475067 modified "2023-10-14" @default.
- W2925475067 title "PD-1/PD-L1 Combinations in Advanced Urothelial Cancer: Rationale and Current Clinical Trials" @default.
- W2925475067 cites W1595951835 @default.
- W2925475067 cites W1849671624 @default.
- W2925475067 cites W1872256430 @default.
- W2925475067 cites W1889335134 @default.
- W2925475067 cites W1995519355 @default.
- W2925475067 cites W2001498331 @default.
- W2925475067 cites W2011458181 @default.
- W2925475067 cites W2018968534 @default.
- W2925475067 cites W2023003954 @default.
- W2925475067 cites W2026426963 @default.
- W2925475067 cites W2056893124 @default.
- W2925475067 cites W2069624577 @default.
- W2925475067 cites W2079315541 @default.
- W2925475067 cites W2083991703 @default.
- W2925475067 cites W2097288420 @default.
- W2925475067 cites W2099854994 @default.
- W2925475067 cites W2103056503 @default.
- W2925475067 cites W2107598346 @default.
- W2925475067 cites W2108026478 @default.
- W2925475067 cites W2110305039 @default.
- W2925475067 cites W2112601576 @default.
- W2925475067 cites W2119897005 @default.
- W2925475067 cites W2121080857 @default.
- W2925475067 cites W2130473166 @default.
- W2925475067 cites W2131620884 @default.
- W2925475067 cites W2136859769 @default.
- W2925475067 cites W2163895585 @default.
- W2925475067 cites W2166662937 @default.
- W2925475067 cites W2179438671 @default.
- W2925475067 cites W2189192330 @default.
- W2925475067 cites W2197259749 @default.
- W2925475067 cites W2257916459 @default.
- W2925475067 cites W2263759961 @default.
- W2925475067 cites W2279561773 @default.
- W2925475067 cites W2289712604 @default.
- W2925475067 cites W2292383635 @default.
- W2925475067 cites W2294356527 @default.
- W2925475067 cites W2329974159 @default.
- W2925475067 cites W2336635113 @default.
- W2925475067 cites W2347101381 @default.
- W2925475067 cites W2400328547 @default.
- W2925475067 cites W2414977199 @default.
- W2925475067 cites W2464620827 @default.
- W2925475067 cites W2473162054 @default.
- W2925475067 cites W2483319193 @default.
- W2925475067 cites W2516271598 @default.
- W2925475067 cites W2516383294 @default.
- W2925475067 cites W2531373072 @default.
- W2925475067 cites W2546607321 @default.
- W2925475067 cites W2556766021 @default.
- W2925475067 cites W2559804019 @default.
- W2925475067 cites W2587048937 @default.
- W2925475067 cites W2591674407 @default.
- W2925475067 cites W2597542073 @default.
- W2925475067 cites W2599926746 @default.
- W2925475067 cites W2602595893 @default.
- W2925475067 cites W2604049989 @default.
- W2925475067 cites W2617848354 @default.
- W2925475067 cites W2624266490 @default.
- W2925475067 cites W2703678370 @default.
- W2925475067 cites W2740715544 @default.
- W2925475067 cites W2742188140 @default.
- W2925475067 cites W2745586357 @default.
- W2925475067 cites W2749090664 @default.
- W2925475067 cites W2758413282 @default.
- W2925475067 cites W2760638321 @default.
- W2925475067 cites W2761139137 @default.
- W2925475067 cites W2765731201 @default.
- W2925475067 cites W2766430096 @default.
- W2925475067 cites W2766860384 @default.
- W2925475067 cites W2771637939 @default.
- W2925475067 cites W2774605139 @default.
- W2925475067 cites W2775570559 @default.
- W2925475067 cites W2780238408 @default.
- W2925475067 cites W2781525129 @default.
- W2925475067 cites W2790597879 @default.
- W2925475067 cites W2791719684 @default.
- W2925475067 cites W2794343662 @default.
- W2925475067 cites W2917837889 @default.
- W2925475067 cites W4237107236 @default.
- W2925475067 doi "https://doi.org/10.1016/j.clgc.2019.03.009" @default.
- W2925475067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31005473" @default.
- W2925475067 hasPublicationYear "2019" @default.
- W2925475067 type Work @default.
- W2925475067 sameAs 2925475067 @default.
- W2925475067 citedByCount "9" @default.
- W2925475067 countsByYear W29254750672019 @default.
- W2925475067 countsByYear W29254750672020 @default.
- W2925475067 countsByYear W29254750672021 @default.
- W2925475067 countsByYear W29254750672022 @default.
- W2925475067 crossrefType "journal-article" @default.