Matches in SemOpenAlex for { <https://semopenalex.org/work/W292570524> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W292570524 endingPage "148" @default.
- W292570524 startingPage "145" @default.
- W292570524 abstract "Immune therapies such as intravenous immunoglobulin (IVIG) and plasma exchange (PLEX) are first line in the treatment of worsening myasthenia gravis. Although PLEX is favored in myasthenic crisis, IVIG is increasingly used in exacerbations due to cost and ease of administration.To review and critically assess current evidence on the effects of IVIG and PLEX on functional outcomes in patients with worsening myasthenia gravis.A structured critical appraisal was conducted on the objective topic. This included a creation of a structured question based on a clinical scenario, comprehensive literature search, selection of evidence for review, and critical appraisal of selected evidence. Evidence was summarized and commentary provided. Participants included consultant and resident neurologists, a medical librarian, clinical epidemiologists, and content experts in the field of neuromuscular neurology.A single-blinded, randomized-controlled trial that compared IVIG and PLEX in 84 patients with worsening myasthenia gravis was selected for review. Primary outcome measure was functional status at 14 days after treatment, as assessed by the Quantitative Myasthenia Gravis Score. Change in Quantitative Myasthenia Gravis Score at day 14 for all subjects was 4.0, without statistically significant differences between IVIG and PLEX groups.IVIG and PLEX are equally effective in worsening myasthenia gravis. Treatment decisions may depend on several variables, including presence of respiratory distress, medical comorbidities, access to medication, and cost. PLEX will likely remain the treatment of choice in true myasthenic crisis." @default.
- W292570524 created "2016-06-24" @default.
- W292570524 creator A5000079573 @default.
- W292570524 creator A5008002660 @default.
- W292570524 creator A5033052761 @default.
- W292570524 creator A5034553945 @default.
- W292570524 creator A5044275701 @default.
- W292570524 creator A5065892224 @default.
- W292570524 creator A5068257247 @default.
- W292570524 creator A5082395750 @default.
- W292570524 date "2015-05-01" @default.
- W292570524 modified "2023-09-27" @default.
- W292570524 title "IVIG Versus PLEX in the Treatment of Worsening Myasthenia Gravis" @default.
- W292570524 cites W1545453083 @default.
- W292570524 cites W1617366981 @default.
- W292570524 cites W1971022805 @default.
- W292570524 cites W1979470935 @default.
- W292570524 cites W1983468718 @default.
- W292570524 cites W1992035277 @default.
- W292570524 cites W2109608985 @default.
- W292570524 cites W2132499360 @default.
- W292570524 cites W2161691440 @default.
- W292570524 cites W2332714133 @default.
- W292570524 doi "https://doi.org/10.1097/nrl.0000000000000026" @default.
- W292570524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25970838" @default.
- W292570524 hasPublicationYear "2015" @default.
- W292570524 type Work @default.
- W292570524 sameAs 292570524 @default.
- W292570524 citedByCount "21" @default.
- W292570524 countsByYear W2925705242015 @default.
- W292570524 countsByYear W2925705242017 @default.
- W292570524 countsByYear W2925705242018 @default.
- W292570524 countsByYear W2925705242019 @default.
- W292570524 countsByYear W2925705242020 @default.
- W292570524 countsByYear W2925705242021 @default.
- W292570524 countsByYear W2925705242022 @default.
- W292570524 countsByYear W2925705242023 @default.
- W292570524 crossrefType "journal-article" @default.
- W292570524 hasAuthorship W292570524A5000079573 @default.
- W292570524 hasAuthorship W292570524A5008002660 @default.
- W292570524 hasAuthorship W292570524A5033052761 @default.
- W292570524 hasAuthorship W292570524A5034553945 @default.
- W292570524 hasAuthorship W292570524A5044275701 @default.
- W292570524 hasAuthorship W292570524A5065892224 @default.
- W292570524 hasAuthorship W292570524A5068257247 @default.
- W292570524 hasAuthorship W292570524A5082395750 @default.
- W292570524 hasConcept C118552586 @default.
- W292570524 hasConcept C126322002 @default.
- W292570524 hasConcept C142724271 @default.
- W292570524 hasConcept C152541439 @default.
- W292570524 hasConcept C159654299 @default.
- W292570524 hasConcept C16568411 @default.
- W292570524 hasConcept C168563851 @default.
- W292570524 hasConcept C177713679 @default.
- W292570524 hasConcept C1862650 @default.
- W292570524 hasConcept C187212893 @default.
- W292570524 hasConcept C203014093 @default.
- W292570524 hasConcept C204787440 @default.
- W292570524 hasConcept C2778105408 @default.
- W292570524 hasConcept C2778842783 @default.
- W292570524 hasConcept C535046627 @default.
- W292570524 hasConcept C71924100 @default.
- W292570524 hasConceptScore W292570524C118552586 @default.
- W292570524 hasConceptScore W292570524C126322002 @default.
- W292570524 hasConceptScore W292570524C142724271 @default.
- W292570524 hasConceptScore W292570524C152541439 @default.
- W292570524 hasConceptScore W292570524C159654299 @default.
- W292570524 hasConceptScore W292570524C16568411 @default.
- W292570524 hasConceptScore W292570524C168563851 @default.
- W292570524 hasConceptScore W292570524C177713679 @default.
- W292570524 hasConceptScore W292570524C1862650 @default.
- W292570524 hasConceptScore W292570524C187212893 @default.
- W292570524 hasConceptScore W292570524C203014093 @default.
- W292570524 hasConceptScore W292570524C204787440 @default.
- W292570524 hasConceptScore W292570524C2778105408 @default.
- W292570524 hasConceptScore W292570524C2778842783 @default.
- W292570524 hasConceptScore W292570524C535046627 @default.
- W292570524 hasConceptScore W292570524C71924100 @default.
- W292570524 hasIssue "5" @default.
- W292570524 hasLocation W2925705241 @default.
- W292570524 hasLocation W2925705242 @default.
- W292570524 hasOpenAccess W292570524 @default.
- W292570524 hasPrimaryLocation W2925705241 @default.
- W292570524 hasRelatedWork W2000967514 @default.
- W292570524 hasRelatedWork W2396962048 @default.
- W292570524 hasRelatedWork W2429336935 @default.
- W292570524 hasRelatedWork W2492545249 @default.
- W292570524 hasRelatedWork W2617809749 @default.
- W292570524 hasRelatedWork W2626360578 @default.
- W292570524 hasRelatedWork W31656499 @default.
- W292570524 hasRelatedWork W75008956 @default.
- W292570524 hasRelatedWork W1992549433 @default.
- W292570524 hasRelatedWork W2183097363 @default.
- W292570524 hasVolume "19" @default.
- W292570524 isParatext "false" @default.
- W292570524 isRetracted "false" @default.
- W292570524 magId "292570524" @default.
- W292570524 workType "article" @default.