Matches in SemOpenAlex for { <https://semopenalex.org/work/W2926030672> ?p ?o ?g. }
- W2926030672 endingPage "1067" @default.
- W2926030672 startingPage "1057" @default.
- W2926030672 abstract "Radix Cyathulae officinalis Kuan, one of the most well-known Chinese medicine, is widely used for invigorating livers and kidneys. The aim of this study is to investigate the hepatoprotective effects of polysaccharide from Radix Cyathulae officinalis Kuan (RCPS) against CCl4-induced liver damage in rat. In vivo experiment showed that oral administrated of RCPS significantly decreased the production of ALT, AST, ALP, LDH, TNF-α, IL-6, IL-1β, MDA in serum, and reduced the expression of TLR4, P-iκBα, iκBα, NF-κBp65 in hepatic tissue. RCPS pretreatment also increased antioxidant enzyme activities Superoxide dismutase (SOD), Glutathione peroxidase (GSH-PX) and non-enzyme antioxidants glutathione (GSH), total antioxidant capacity (T-AOC) compared with CCl4-induced. Furthermore, hepatic histopathological changes induced by CCl4 were significantly normalized by RCPS pretreatment. These results indicated that RCPS had hepatoprotective effect against CCl4-induced acute liver injure." @default.
- W2926030672 created "2019-04-11" @default.
- W2926030672 creator A5005100980 @default.
- W2926030672 creator A5013465321 @default.
- W2926030672 creator A5040692430 @default.
- W2926030672 creator A5053526025 @default.
- W2926030672 creator A5059085853 @default.
- W2926030672 creator A5059736541 @default.
- W2926030672 creator A5068247833 @default.
- W2926030672 creator A5090685065 @default.
- W2926030672 date "2019-07-01" @default.
- W2926030672 modified "2023-09-25" @default.
- W2926030672 title "Hepatoprotective effect of a polysaccharide from Radix Cyathulae officinalis Kuan against CCl4-induced acute liver injury in rat" @default.
- W2926030672 cites W1964738530 @default.
- W2926030672 cites W1965729497 @default.
- W2926030672 cites W1966875259 @default.
- W2926030672 cites W1970919692 @default.
- W2926030672 cites W1975150071 @default.
- W2926030672 cites W1979338362 @default.
- W2926030672 cites W1979487735 @default.
- W2926030672 cites W1988619101 @default.
- W2926030672 cites W1989799357 @default.
- W2926030672 cites W2004187431 @default.
- W2926030672 cites W2004418703 @default.
- W2926030672 cites W2005322560 @default.
- W2926030672 cites W2012365838 @default.
- W2926030672 cites W2013049586 @default.
- W2926030672 cites W2013554848 @default.
- W2926030672 cites W2014973641 @default.
- W2926030672 cites W2016575086 @default.
- W2926030672 cites W2017152429 @default.
- W2926030672 cites W2021822137 @default.
- W2926030672 cites W2031784846 @default.
- W2926030672 cites W2033023829 @default.
- W2926030672 cites W2033390870 @default.
- W2926030672 cites W2036862601 @default.
- W2926030672 cites W2038581926 @default.
- W2926030672 cites W2058101404 @default.
- W2926030672 cites W2060403320 @default.
- W2926030672 cites W2064795020 @default.
- W2926030672 cites W2071100703 @default.
- W2926030672 cites W2084839157 @default.
- W2926030672 cites W2089704313 @default.
- W2926030672 cites W2092179037 @default.
- W2926030672 cites W2093267024 @default.
- W2926030672 cites W2100155786 @default.
- W2926030672 cites W2104109524 @default.
- W2926030672 cites W2104702470 @default.
- W2926030672 cites W2109738215 @default.
- W2926030672 cites W2110315597 @default.
- W2926030672 cites W2163122663 @default.
- W2926030672 cites W2171401894 @default.
- W2926030672 cites W2176389459 @default.
- W2926030672 cites W2177602167 @default.
- W2926030672 cites W2408239743 @default.
- W2926030672 cites W2473465820 @default.
- W2926030672 cites W2572784418 @default.
- W2926030672 cites W2783165084 @default.
- W2926030672 cites W2801932266 @default.
- W2926030672 cites W2903362674 @default.
- W2926030672 cites W4237800005 @default.
- W2926030672 doi "https://doi.org/10.1016/j.ijbiomac.2019.04.018" @default.
- W2926030672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30954593" @default.
- W2926030672 hasPublicationYear "2019" @default.
- W2926030672 type Work @default.
- W2926030672 sameAs 2926030672 @default.
- W2926030672 citedByCount "26" @default.
- W2926030672 countsByYear W29260306722019 @default.
- W2926030672 countsByYear W29260306722020 @default.
- W2926030672 countsByYear W29260306722021 @default.
- W2926030672 countsByYear W29260306722022 @default.
- W2926030672 countsByYear W29260306722023 @default.
- W2926030672 crossrefType "journal-article" @default.
- W2926030672 hasAuthorship W2926030672A5005100980 @default.
- W2926030672 hasAuthorship W2926030672A5013465321 @default.
- W2926030672 hasAuthorship W2926030672A5040692430 @default.
- W2926030672 hasAuthorship W2926030672A5053526025 @default.
- W2926030672 hasAuthorship W2926030672A5059085853 @default.
- W2926030672 hasAuthorship W2926030672A5059736541 @default.
- W2926030672 hasAuthorship W2926030672A5068247833 @default.
- W2926030672 hasAuthorship W2926030672A5090685065 @default.
- W2926030672 hasConcept C102124568 @default.
- W2926030672 hasConcept C165069038 @default.
- W2926030672 hasConcept C178790620 @default.
- W2926030672 hasConcept C181199279 @default.
- W2926030672 hasConcept C185592680 @default.
- W2926030672 hasConcept C2775838275 @default.
- W2926030672 hasConcept C2776637226 @default.
- W2926030672 hasConcept C2777359374 @default.
- W2926030672 hasConcept C2778004101 @default.
- W2926030672 hasConcept C2778401633 @default.
- W2926030672 hasConcept C2778760513 @default.
- W2926030672 hasConcept C2779091547 @default.
- W2926030672 hasConcept C2780886089 @default.
- W2926030672 hasConcept C538909803 @default.
- W2926030672 hasConcept C55493867 @default.
- W2926030672 hasConcept C556039675 @default.
- W2926030672 hasConcept C59822182 @default.