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• W2927214673 abstract "Objectives This study retrospectively evaluated the prognostic performance of the ultrasound elastographic Q‐analysis score (EQS) combined with the Prostate Imaging Reporting and Data System (PI‐RADS) for malignancy risk stratification in prostate nodules based on transrectal ultrasound–magnetic resonance imaging fusion imaging. Methods Sixty‐two patients who were suspected to have PCa between October 2017 and May 2018 in our hospital were retrospectively evaluated. The performance of the EQS and PI‐RADS was evaluated by patients’ receiver operating characteristic curves in differentiating malignant and benign prostate nodules. The combination of the EQS and PI‐RADS methods for prostate imaging was evaluated. Results Sixty‐two prostate nodules in 62 patients were included. All of the patients underwent biopsy; 29 cases were prostate cancer, and the rest were benign prostate lesions. Both the EQS and PI‐RADS were significantly higher in malignant nodules than in benign nodules. The sensitivity, specificity, area under the curve, positive likelihood ratio, negative likelihood ratio, positive predictive value, negative predictive value, and Youden index of an EQS cutoff of 2.05 were 86.2%, 81.8%, 85.9%, 4.73, 0.169, 80.6%, 87.1%, and 68%, respectively. The corresponding numbers for a PI‐RADS cutoff of 4 were 82.7%, 69.7%, 84.2%, 2.72, 0.25, 70.6%, 82.1%, and 52.4%. The “tandem” method had a higher diagnostic specificity (87.9%), positive likelihood ratio (6.55), and positive predictive value (85.1%). The “parallel” method had a higher diagnostic sensitivity (96.5%), negative likelihood ratio (0.06), and negative predictive value (95.2%). Conclusions both the EQS and PI‐RADS had good diagnostic performance in differentiating between malignant and benign prostate lesions. The combination of the EQS and PI‐RADS improved the diagnostic performance to a certain degree." @default.
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• W2927214673 date "2019-04-01" @default.
• W2927214673 modified "2023-10-18" @default.
• W2927214673 title "Evaluation of the Performance of the Ultrasound (US) Elastographic Q‐Analysis Score Combined With the Prostate Imaging Reporting and Data System for Malignancy Risk Stratification in Prostate Nodules Based on Transrectal US–Magnetic Resonance Imaging Fusion Imaging" @default.
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• W2927214673 doi "https://doi.org/10.1002/jum.15005" @default.
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