Matches in SemOpenAlex for { <https://semopenalex.org/work/W2928355220> ?p ?o ?g. }
- W2928355220 endingPage "e14855" @default.
- W2928355220 startingPage "e14855" @default.
- W2928355220 abstract "Abstract Numerous studies have investigated the association between ALDH2 gene rs671G>A polymorphism and various cancer type in Asians. However, the results remain inconclusive. We conducted a comprehensive meta-analysis including 63 articles with 66 studies containing 25,682 cases and 47,455 controls retrieved by searching PubMed and Embase electronic databases up to March 5, 2018. Pooled results indicated that ALDH2 gene rs671 polymorphism was significantly associated with the overall cancer risk in Asians (homozygous model: odds ratio [OR] = 0.85, 95% confidence interval [CI] = 0.72–0.99, P = .042; heterozygous model: OR = 1.32, 95% CI = 1.14–1.52, P < .001; recessive model: OR = 0.73, 95% CI = 0.60–0.88, P = .001; dominant model: OR = 1.32, 95% CI = 1.16–1.51, P < .001; and allele comparison model: OR = 1.11, 95% CI = 1.03–1.19, P = .004), especially in esophageal cancer and among the Chinese and the Japanese. Our results suggest that ALDH2 rs671 polymorphism is associated with the overall cancer risk in Asians. Well-designed prospective studies with more information about gene–environment interaction, such as drinking, should be conducted to validate our findings." @default.
- W2928355220 created "2019-04-11" @default.
- W2928355220 creator A5003164343 @default.
- W2928355220 creator A5004260686 @default.
- W2928355220 creator A5019645840 @default.
- W2928355220 creator A5024873810 @default.
- W2928355220 creator A5035853481 @default.
- W2928355220 date "2019-03-01" @default.
- W2928355220 modified "2023-09-27" @default.
- W2928355220 title "Effect of ALDH2 polymorphism on cancer risk in Asians" @default.
- W2928355220 cites W1529058556 @default.
- W2928355220 cites W1963498395 @default.
- W2928355220 cites W1969275265 @default.
- W2928355220 cites W1974523657 @default.
- W2928355220 cites W1987466914 @default.
- W2928355220 cites W1992837744 @default.
- W2928355220 cites W1995249037 @default.
- W2928355220 cites W2006501056 @default.
- W2928355220 cites W2006612367 @default.
- W2928355220 cites W2007869964 @default.
- W2928355220 cites W2008337584 @default.
- W2928355220 cites W2012696777 @default.
- W2928355220 cites W2015481191 @default.
- W2928355220 cites W2018437082 @default.
- W2928355220 cites W2019937184 @default.
- W2928355220 cites W2027420517 @default.
- W2928355220 cites W2028377786 @default.
- W2928355220 cites W2030048339 @default.
- W2928355220 cites W2032067170 @default.
- W2928355220 cites W2034145052 @default.
- W2928355220 cites W2045712143 @default.
- W2928355220 cites W2045966127 @default.
- W2928355220 cites W2054743010 @default.
- W2928355220 cites W2064057901 @default.
- W2928355220 cites W2065737378 @default.
- W2928355220 cites W2070663300 @default.
- W2928355220 cites W2072232646 @default.
- W2928355220 cites W2073226547 @default.
- W2928355220 cites W2075079870 @default.
- W2928355220 cites W2079348404 @default.
- W2928355220 cites W2081152773 @default.
- W2928355220 cites W2090871471 @default.
- W2928355220 cites W2094286829 @default.
- W2928355220 cites W2094652685 @default.
- W2928355220 cites W2100770142 @default.
- W2928355220 cites W2101546034 @default.
- W2928355220 cites W2102141030 @default.
- W2928355220 cites W2107063554 @default.
- W2928355220 cites W2107328434 @default.
- W2928355220 cites W2107493000 @default.
- W2928355220 cites W2109970687 @default.
- W2928355220 cites W2110283622 @default.
- W2928355220 cites W2115775303 @default.
- W2928355220 cites W2119982549 @default.
- W2928355220 cites W2125386601 @default.
- W2928355220 cites W2137376330 @default.
- W2928355220 cites W2138288952 @default.
- W2928355220 cites W2139874167 @default.
- W2928355220 cites W2149389947 @default.
- W2928355220 cites W2150092781 @default.
- W2928355220 cites W2151028908 @default.
- W2928355220 cites W2154272355 @default.
- W2928355220 cites W2157823046 @default.
- W2928355220 cites W2163059250 @default.
- W2928355220 cites W2165373217 @default.
- W2928355220 cites W2169422423 @default.
- W2928355220 cites W2268784222 @default.
- W2928355220 cites W2272984102 @default.
- W2928355220 cites W2307148236 @default.
- W2928355220 cites W2312194601 @default.
- W2928355220 cites W2318048476 @default.
- W2928355220 cites W2318460837 @default.
- W2928355220 cites W2523056957 @default.
- W2928355220 cites W2564149251 @default.
- W2928355220 cites W2566061455 @default.
- W2928355220 cites W2592424621 @default.
- W2928355220 cites W2592675475 @default.
- W2928355220 cites W2593335961 @default.
- W2928355220 cites W2611064870 @default.
- W2928355220 cites W2889646458 @default.
- W2928355220 cites W4231376406 @default.
- W2928355220 doi "https://doi.org/10.1097/md.0000000000014855" @default.
- W2928355220 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6456109" @default.
- W2928355220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30921184" @default.
- W2928355220 hasPublicationYear "2019" @default.
- W2928355220 type Work @default.
- W2928355220 sameAs 2928355220 @default.
- W2928355220 citedByCount "18" @default.
- W2928355220 countsByYear W29283552202020 @default.
- W2928355220 countsByYear W29283552202021 @default.
- W2928355220 countsByYear W29283552202022 @default.
- W2928355220 countsByYear W29283552202023 @default.
- W2928355220 crossrefType "journal-article" @default.
- W2928355220 hasAuthorship W2928355220A5003164343 @default.
- W2928355220 hasAuthorship W2928355220A5004260686 @default.
- W2928355220 hasAuthorship W2928355220A5019645840 @default.
- W2928355220 hasAuthorship W2928355220A5024873810 @default.
- W2928355220 hasAuthorship W2928355220A5035853481 @default.