Matches in SemOpenAlex for { <https://semopenalex.org/work/W2928540575> ?p ?o ?g. }
- W2928540575 endingPage "18" @default.
- W2928540575 startingPage "8" @default.
- W2928540575 abstract "Plant lectins are non-immunoglobin in nature and bind to the carbohydrate moiety of the glycoconjugates without altering any of the recognized glycosyl ligands. Plant lectins have found applications as cancer biomarkers for recognizing the malignant tumor cells for the diagnosis and prognosis of cancer. Interestingly, plant lectins contribute to inducing cell death through autophagy and apoptosis, indicating their potential implication in cancer inhibitory mechanism. In the present review, anticancer activities of major plant lectins have been documented, with a detailed focus on the signaling circuit for the possible molecular targeted cancer therapy. In this context, several lectins have exhibited preclinical and clinical significance, driving toward therapeutic potential in cancer treatment. Moreover, several plant lectins induce immunomodulatory activities, and therefore, novel strategies have been established from preclinical and clinical investigations for the development of combinatorial treatment consisting of immunotherapy along with other anticancer therapies. Although the application of plant lectins in cancer is still in very preliminary stage, advanced high-throughput technology could pave the way for the development of lectin-based complimentary medicine for cancer treatment." @default.
- W2928540575 created "2019-04-11" @default.
- W2928540575 creator A5002224920 @default.
- W2928540575 creator A5002697297 @default.
- W2928540575 creator A5013562692 @default.
- W2928540575 creator A5017183210 @default.
- W2928540575 creator A5031149055 @default.
- W2928540575 creator A5034034338 @default.
- W2928540575 creator A5035317652 @default.
- W2928540575 creator A5039599940 @default.
- W2928540575 creator A5040431431 @default.
- W2928540575 creator A5043450835 @default.
- W2928540575 creator A5054304436 @default.
- W2928540575 creator A5055574140 @default.
- W2928540575 creator A5082195070 @default.
- W2928540575 date "2019-06-01" @default.
- W2928540575 modified "2023-10-16" @default.
- W2928540575 title "Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death" @default.
- W2928540575 cites W1182461782 @default.
- W2928540575 cites W1486797165 @default.
- W2928540575 cites W1619470453 @default.
- W2928540575 cites W1818742901 @default.
- W2928540575 cites W1963814231 @default.
- W2928540575 cites W1964113011 @default.
- W2928540575 cites W1965857762 @default.
- W2928540575 cites W1968638592 @default.
- W2928540575 cites W1971102108 @default.
- W2928540575 cites W1973200693 @default.
- W2928540575 cites W1973410601 @default.
- W2928540575 cites W1974269635 @default.
- W2928540575 cites W1974304686 @default.
- W2928540575 cites W1976291093 @default.
- W2928540575 cites W1976921001 @default.
- W2928540575 cites W1979886186 @default.
- W2928540575 cites W1980736687 @default.
- W2928540575 cites W1981559647 @default.
- W2928540575 cites W1982569158 @default.
- W2928540575 cites W1983824250 @default.
- W2928540575 cites W1984063962 @default.
- W2928540575 cites W1984790178 @default.
- W2928540575 cites W1985700742 @default.
- W2928540575 cites W1987740582 @default.
- W2928540575 cites W1988129252 @default.
- W2928540575 cites W1990034676 @default.
- W2928540575 cites W1994043502 @default.
- W2928540575 cites W2000324597 @default.
- W2928540575 cites W2002425948 @default.
- W2928540575 cites W2004554470 @default.
- W2928540575 cites W2005126852 @default.
- W2928540575 cites W2005644395 @default.
- W2928540575 cites W2006808589 @default.
- W2928540575 cites W2007460937 @default.
- W2928540575 cites W2008440244 @default.
- W2928540575 cites W2009563838 @default.
- W2928540575 cites W2013645284 @default.
- W2928540575 cites W2015892282 @default.
- W2928540575 cites W2018958401 @default.
- W2928540575 cites W2021575804 @default.
- W2928540575 cites W2022695112 @default.
- W2928540575 cites W2022993390 @default.
- W2928540575 cites W2023177232 @default.
- W2928540575 cites W2024551447 @default.
- W2928540575 cites W2038348721 @default.
- W2928540575 cites W2039549095 @default.
- W2928540575 cites W2041813014 @default.
- W2928540575 cites W2041912685 @default.
- W2928540575 cites W2042784874 @default.
- W2928540575 cites W2043260389 @default.
- W2928540575 cites W2052121783 @default.
- W2928540575 cites W2055070114 @default.
- W2928540575 cites W2056389789 @default.
- W2928540575 cites W2063469641 @default.
- W2928540575 cites W2064106041 @default.
- W2928540575 cites W2066554820 @default.
- W2928540575 cites W2072753690 @default.
- W2928540575 cites W2079240469 @default.
- W2928540575 cites W2079260045 @default.
- W2928540575 cites W2082094906 @default.
- W2928540575 cites W2082992597 @default.
- W2928540575 cites W2085704486 @default.
- W2928540575 cites W2085760513 @default.
- W2928540575 cites W2093799704 @default.
- W2928540575 cites W2095456353 @default.
- W2928540575 cites W2101312011 @default.
- W2928540575 cites W2102135397 @default.
- W2928540575 cites W2103818937 @default.
- W2928540575 cites W2104436843 @default.
- W2928540575 cites W2114508131 @default.
- W2928540575 cites W2118054188 @default.
- W2928540575 cites W2121746611 @default.
- W2928540575 cites W2122179532 @default.
- W2928540575 cites W2124539321 @default.
- W2928540575 cites W2128129742 @default.
- W2928540575 cites W2133287475 @default.
- W2928540575 cites W2136942110 @default.
- W2928540575 cites W2141589586 @default.
- W2928540575 cites W2142286061 @default.
- W2928540575 cites W2144484656 @default.