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• W2928723193 startingPage "1934578X0600101" @default.
• W2928723193 abstract "Boropinic acid and other natural prenyloxycinnamic and benzoic acids were easily synthesized in high yield by a two-step sequence from the corresponding p-hydroxy aromatic acids and were assayed for radical scavenging activity using the DPPH test and for inhibition of enzymatic lipid peroxidation mediated by soybean 5-lipoxygenase. Compared to other acids and to known antioxidant compounds like BHT, Trolox and ascorbic acid, boropinic acid was far more active in the lipoxygenase test (IC 50 = 7.6 ng/mL, p < 0.05). The recorded inhibition value suggested that boropinic acid acted as an enzyme inhibitor rather than a mere radical or peroxide scavenger. This hypothesis was confirmed by studying the interaction between boropinic acid and soybean 5-lipoxygenase by molecular modelling techniques." @default.
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• W2928723193 date "2006-12-01" @default.
• W2928723193 modified "2023-09-26" @default.
• W2928723193 title "Lipoxygenase Inhibitory Activity of Boropinic Acid, Active Principle of Boronia Pinnata" @default.
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• W2928723193 doi "https://doi.org/10.1177/1934578x0600101214" @default.
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