FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2929478850> ?p ?o ?g. }

• W2929478850 endingPage "1640" @default.
• W2929478850 startingPage "1640" @default.
• W2929478850 abstract "The epithelial–mesenchymal transition (EMT) process is known to play an essential role in tumor progression, metastasis and resistance to therapy. This report evaluated the prognostic value of co-expression of the receptor for prolactin (PRLR), a suppressor of EMT, and the receptors for transforming growth factor β (TGFβRI and TGFβRII), an inducer of EMT, in association with different clinicopathological parameters using TMA of 102 breast cancer patients and publicly available data on breast cancer patients. Interestingly, the results revealed that malignant tissues had significantly lower levels of concomitant protein expression of these receptors in comparison to normal/benign breast tissue. In addition, a higher level of concomitant expression was also observed in less aggressive breast cancer phenotypes, including low grade tumors, luminal breast cancer subtype, and less advanced stages of the disease (lymph node negative and early stages). Moreover, the results also showed that the expression of a gene signature composed of PRLR/TGFβRI/TGFβRII correlates more with differentiated grade I tumors, and identified a subset of patients showing better survival outcomes evident in luminal B and HER-2 enriched molecular subtypes. Together, these results indicate that loss of the co-expression of PRLR, TGFβRI and TGFβRII is indicative of aggressiveness and poor patient survival outcomes in breast cancer." @default.
• W2929478850 created "2019-04-11" @default.
• W2929478850 creator A5016667677 @default.
• W2929478850 creator A5025132882 @default.
• W2929478850 creator A5061095833 @default.
• W2929478850 creator A5085866897 @default.
• W2929478850 creator A5091794314 @default.
• W2929478850 date "2019-04-02" @default.
• W2929478850 modified "2023-09-27" @default.
• W2929478850 title "Concomitant Expression of Prolactin Receptor and TGFβ Receptors in Breast Cancer: Association with Less Aggressive Phenotype and Favorable Patient Outcome" @default.
• W2929478850 cites W1563762782 @default.
• W2929478850 cites W1565561072 @default.
• W2929478850 cites W1627068912 @default.
• W2929478850 cites W1966857167 @default.
• W2929478850 cites W1986724703 @default.
• W2929478850 cites W1988925715 @default.
• W2929478850 cites W1997387647 @default.
• W2929478850 cites W2035119913 @default.
• W2929478850 cites W2044702943 @default.
• W2929478850 cites W2048477123 @default.
• W2929478850 cites W2064800534 @default.
• W2929478850 cites W2069524101 @default.
• W2929478850 cites W2074981026 @default.
• W2929478850 cites W2111564953 @default.
• W2929478850 cites W2128920415 @default.
• W2929478850 cites W2132893003 @default.
• W2929478850 cites W2139206204 @default.
• W2929478850 cites W2143584784 @default.
• W2929478850 cites W2163775578 @default.
• W2929478850 cites W2168026694 @default.
• W2929478850 cites W2301343927 @default.
• W2929478850 cites W2325314951 @default.
• W2929478850 cites W2479207946 @default.
• W2929478850 cites W2484544705 @default.
• W2929478850 cites W2555771555 @default.
• W2929478850 cites W2621567555 @default.
• W2929478850 cites W2767132912 @default.
• W2929478850 cites W2885375398 @default.
• W2929478850 cites W2897243059 @default.
• W2929478850 cites W4211233744 @default.
• W2929478850 doi "https://doi.org/10.3390/ijms20071640" @default.
• W2929478850 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6479350" @default.
• W2929478850 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30987013" @default.
• W2929478850 hasPublicationYear "2019" @default.
• W2929478850 type Work @default.
• W2929478850 sameAs 2929478850 @default.
• W2929478850 citedByCount "6" @default.
• W2929478850 countsByYear W29294788502020 @default.
• W2929478850 countsByYear W29294788502021 @default.
• W2929478850 countsByYear W29294788502023 @default.
• W2929478850 crossrefType "journal-article" @default.
• W2929478850 hasAuthorship W2929478850A5016667677 @default.
• W2929478850 hasAuthorship W2929478850A5025132882 @default.
• W2929478850 hasAuthorship W2929478850A5061095833 @default.
• W2929478850 hasAuthorship W2929478850A5085866897 @default.
• W2929478850 hasAuthorship W2929478850A5091794314 @default.
• W2929478850 hasBestOaLocation W29294788501 @default.
• W2929478850 hasConcept C104317684 @default.
• W2929478850 hasConcept C118131993 @default.
• W2929478850 hasConcept C121608353 @default.
• W2929478850 hasConcept C126322002 @default.
• W2929478850 hasConcept C127716648 @default.
• W2929478850 hasConcept C143998085 @default.
• W2929478850 hasConcept C170493617 @default.
• W2929478850 hasConcept C2778229498 @default.
• W2929478850 hasConcept C2779013556 @default.
• W2929478850 hasConcept C2779384505 @default.
• W2929478850 hasConcept C502942594 @default.
• W2929478850 hasConcept C530470458 @default.
• W2929478850 hasConcept C55493867 @default.
• W2929478850 hasConcept C71924100 @default.
• W2929478850 hasConcept C86803240 @default.
• W2929478850 hasConceptScore W2929478850C104317684 @default.
• W2929478850 hasConceptScore W2929478850C118131993 @default.
• W2929478850 hasConceptScore W2929478850C121608353 @default.
• W2929478850 hasConceptScore W2929478850C126322002 @default.
• W2929478850 hasConceptScore W2929478850C127716648 @default.
• W2929478850 hasConceptScore W2929478850C143998085 @default.
• W2929478850 hasConceptScore W2929478850C170493617 @default.
• W2929478850 hasConceptScore W2929478850C2778229498 @default.
• W2929478850 hasConceptScore W2929478850C2779013556 @default.
• W2929478850 hasConceptScore W2929478850C2779384505 @default.
• W2929478850 hasConceptScore W2929478850C502942594 @default.
• W2929478850 hasConceptScore W2929478850C530470458 @default.
• W2929478850 hasConceptScore W2929478850C55493867 @default.
• W2929478850 hasConceptScore W2929478850C71924100 @default.
• W2929478850 hasConceptScore W2929478850C86803240 @default.
• W2929478850 hasFunder F4320321563 @default.
• W2929478850 hasIssue "7" @default.
• W2929478850 hasLocation W29294788501 @default.
• W2929478850 hasLocation W29294788502 @default.
• W2929478850 hasLocation W29294788503 @default.
• W2929478850 hasLocation W29294788504 @default.
• W2929478850 hasOpenAccess W2929478850 @default.
• W2929478850 hasPrimaryLocation W29294788501 @default.
• W2929478850 hasRelatedWork W1499339123 @default.
• W2929478850 hasRelatedWork W1752581403 @default.
• W2929478850 hasRelatedWork W2224319365 @default.

• next