Matches in SemOpenAlex for { <https://semopenalex.org/work/W2930992023> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2930992023 abstract "Bark of Evodiopanax innovans (Araliaceae) was subjected to membrane activity-guided extraction and chromatographic fractionation. The potency to interact with lipid membranes and change their fluidity was determined by measuring fluorescence polarization of liposomal and cell membranes. Plant preparations, including the MeOH extract and the specified fraction, reduced the fluidity of model biomembranes prepared with different phospholipids and cholesterol. Further purification led to the isolation of maltol 3- O-β-glucopyranoside, which inhibited tumor cell growth and platelet aggregation, together with rigidifying the cell membranes as well as the membrane-active antitumor compound (-)-epigallocatechin gallate and doxorubicin. The isolate at 100 μM and 1.0 mM showed growth inhibition of 13–49% against tumor cells cultured for 24 and 48 h. At 1.8–3.6 mM, it also produced 50% inhibition of platelet aggregation induced by collagen, adenosine 5′-diphosphate and thrombin. E. innovans is considered as a medicinal plant containing a potent bioactive constituent that exerts antiproliferative and antiplatelet effects through interaction with cell membranes to modify their fluidity." @default.
- W2930992023 created "2019-04-11" @default.
- W2930992023 creator A5015719192 @default.
- W2930992023 creator A5021516624 @default.
- W2930992023 creator A5023049186 @default.
- W2930992023 creator A5047973207 @default.
- W2930992023 creator A5085766889 @default.
- W2930992023 date "2008-05-01" @default.
- W2930992023 modified "2023-09-23" @default.
- W2930992023 title "Membrane Activity-Guided Isolation of Antiproliferative and Antiplatelet Constituent from Evodiopanax Innovans" @default.
- W2930992023 cites W149534088 @default.
- W2930992023 cites W1501554895 @default.
- W2930992023 cites W1965149714 @default.
- W2930992023 cites W1965944459 @default.
- W2930992023 cites W1967047695 @default.
- W2930992023 cites W1972110364 @default.
- W2930992023 cites W1978284036 @default.
- W2930992023 cites W1985744477 @default.
- W2930992023 cites W1995740410 @default.
- W2930992023 cites W1999096042 @default.
- W2930992023 cites W2001041922 @default.
- W2930992023 cites W2008923761 @default.
- W2930992023 cites W2012659976 @default.
- W2930992023 cites W2017740538 @default.
- W2930992023 cites W2029228361 @default.
- W2930992023 cites W2031298315 @default.
- W2930992023 cites W2041910443 @default.
- W2930992023 cites W2054514899 @default.
- W2930992023 cites W2058426885 @default.
- W2930992023 cites W2062455220 @default.
- W2930992023 cites W2068518488 @default.
- W2930992023 cites W2078621219 @default.
- W2930992023 cites W2079292424 @default.
- W2930992023 cites W2083596018 @default.
- W2930992023 cites W2099612035 @default.
- W2930992023 cites W2103602167 @default.
- W2930992023 cites W2134746625 @default.
- W2930992023 cites W2147995249 @default.
- W2930992023 cites W2164450230 @default.
- W2930992023 cites W3145614242 @default.
- W2930992023 cites W91452638 @default.
- W2930992023 doi "https://doi.org/10.1177/1934578x0800300525" @default.
- W2930992023 hasPublicationYear "2008" @default.
- W2930992023 type Work @default.
- W2930992023 sameAs 2930992023 @default.
- W2930992023 citedByCount "0" @default.
- W2930992023 crossrefType "journal-article" @default.
- W2930992023 hasAuthorship W2930992023A5015719192 @default.
- W2930992023 hasAuthorship W2930992023A5021516624 @default.
- W2930992023 hasAuthorship W2930992023A5023049186 @default.
- W2930992023 hasAuthorship W2930992023A5047973207 @default.
- W2930992023 hasAuthorship W2930992023A5085766889 @default.
- W2930992023 hasConcept C185592680 @default.
- W2930992023 hasConcept C2775941552 @default.
- W2930992023 hasConcept C556039675 @default.
- W2930992023 hasConcept C71924100 @default.
- W2930992023 hasConcept C86803240 @default.
- W2930992023 hasConcept C89423630 @default.
- W2930992023 hasConcept C98274493 @default.
- W2930992023 hasConceptScore W2930992023C185592680 @default.
- W2930992023 hasConceptScore W2930992023C2775941552 @default.
- W2930992023 hasConceptScore W2930992023C556039675 @default.
- W2930992023 hasConceptScore W2930992023C71924100 @default.
- W2930992023 hasConceptScore W2930992023C86803240 @default.
- W2930992023 hasConceptScore W2930992023C89423630 @default.
- W2930992023 hasConceptScore W2930992023C98274493 @default.
- W2930992023 hasLocation W29309920231 @default.
- W2930992023 hasOpenAccess W2930992023 @default.
- W2930992023 hasPrimaryLocation W29309920231 @default.
- W2930992023 hasRelatedWork W1973134188 @default.
- W2930992023 hasRelatedWork W1998791450 @default.
- W2930992023 hasRelatedWork W2129640336 @default.
- W2930992023 hasRelatedWork W2541791212 @default.
- W2930992023 hasRelatedWork W2795924475 @default.
- W2930992023 hasRelatedWork W2971778984 @default.
- W2930992023 isParatext "false" @default.
- W2930992023 isRetracted "false" @default.
- W2930992023 magId "2930992023" @default.
- W2930992023 workType "article" @default.