FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2931366185> ?p ?o ?g. }

• W2931366185 endingPage "722" @default.
• W2931366185 startingPage "712" @default.
• W2931366185 abstract "The optimal neoadjuvant radiation therapy (RT) dose prior to esophagectomy is unknown. We compared patients receiving lower-dose RT (LD-RT) of 41.4-45 Gy versus those receiving higher-dose RT (HD-RT) of 50-54 Gy.Patients with non-metastatic esophageal or gastroesophageal cancer diagnosed from 2004 to 2015 who underwent neoadjuvant chemoradiation (CRT) followed by esophagectomy were identified using the National Cancer Database (NCDB) and divided into LD-RT and HD-RT groups. Logistic regression was used to evaluate predictors of HD-RT utilization and propensity score matching. Overall survival (OS) was compared between HD-RT and LD-RT groups using Cox regression. Logistic regression was performed with respect to pathologic complete response (pCR), positive surgical margins, postoperative mortality, and readmission rates.We identified 7,996 patients meeting inclusion criteria, of which 5,732 (71.7%) received HD-RT. At median follow-up of 3.3 years, 3-year OS was 48.7% for HD-RT versus 48.4% for LD-RT (P=0.734). pCR rates were 20.3% with HD-RT versus 16.3% with LD-RT [odds ratio (OR) 1.24; 95% CI: 1.06-1.44; P=0.006]. There were no statistically significant differences between HD-RT and LD-RT with respect to positive margins, 90-day postoperative mortality, or readmission rates. In a separate analysis of patients treated with CRT alone and no subsequent esophagectomy, HD-RT was associated with improved OS (HR 0.83; 95% CI: 0.78-0.88; P<0.001).Our analysis suggests that 41.4-45 and 50-54 Gy dose regimens are similar in survival and postoperative outcomes. However, in cases of equivocal resectability, a higher RT dose of 50-54 Gy may be preferred." @default.
• W2931366185 created "2019-04-11" @default.
• W2931366185 creator A5009303158 @default.
• W2931366185 creator A5009435876 @default.
• W2931366185 creator A5016123864 @default.
• W2931366185 creator A5020069509 @default.
• W2931366185 creator A5025056006 @default.
• W2931366185 creator A5044163553 @default.
• W2931366185 creator A5046103656 @default.
• W2931366185 creator A5054489256 @default.
• W2931366185 creator A5089084282 @default.
• W2931366185 date "2019-08-01" @default.
• W2931366185 modified "2023-09-27" @default.
• W2931366185 title "Analyzing the impact of neoadjuvant radiation dose on pathologic response and survival outcomes in esophageal and gastroesophageal cancers" @default.
• W2931366185 cites W1922694287 @default.
• W2931366185 cites W1965749846 @default.
• W2931366185 cites W1983610771 @default.
• W2931366185 cites W2004079062 @default.
• W2931366185 cites W2032043488 @default.
• W2931366185 cites W2053506834 @default.
• W2931366185 cites W2099918668 @default.
• W2931366185 cites W2117223681 @default.
• W2931366185 cites W2127996441 @default.
• W2931366185 cites W2129252535 @default.
• W2931366185 cites W2129292725 @default.
• W2931366185 cites W2136839015 @default.
• W2931366185 cites W2137696504 @default.
• W2931366185 cites W2139525657 @default.
• W2931366185 cites W2154444715 @default.
• W2931366185 cites W2169906597 @default.
• W2931366185 cites W2187716829 @default.
• W2931366185 cites W2307731066 @default.
• W2931366185 cites W2333224485 @default.
• W2931366185 cites W2515733792 @default.
• W2931366185 cites W2603965080 @default.
• W2931366185 cites W2616506302 @default.
• W2931366185 cites W2733330634 @default.
• W2931366185 cites W2756014249 @default.
• W2931366185 cites W2765470263 @default.
• W2931366185 cites W2781525129 @default.
• W2931366185 cites W2917837889 @default.
• W2931366185 cites W4236554935 @default.
• W2931366185 doi "https://doi.org/10.21037/jgo.2019.02.18" @default.
• W2931366185 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6657311" @default.
• W2931366185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31392052" @default.
• W2931366185 hasPublicationYear "2019" @default.
• W2931366185 type Work @default.
• W2931366185 sameAs 2931366185 @default.
• W2931366185 citedByCount "3" @default.
• W2931366185 countsByYear W29313661852021 @default.
• W2931366185 countsByYear W29313661852022 @default.
• W2931366185 crossrefType "journal-article" @default.
• W2931366185 hasAuthorship W2931366185A5009303158 @default.
• W2931366185 hasAuthorship W2931366185A5009435876 @default.
• W2931366185 hasAuthorship W2931366185A5016123864 @default.
• W2931366185 hasAuthorship W2931366185A5020069509 @default.
• W2931366185 hasAuthorship W2931366185A5025056006 @default.
• W2931366185 hasAuthorship W2931366185A5044163553 @default.
• W2931366185 hasAuthorship W2931366185A5046103656 @default.
• W2931366185 hasAuthorship W2931366185A5054489256 @default.
• W2931366185 hasAuthorship W2931366185A5089084282 @default.
• W2931366185 hasBestOaLocation W29313661851 @default.
• W2931366185 hasConcept C121608353 @default.
• W2931366185 hasConcept C126322002 @default.
• W2931366185 hasConcept C143998085 @default.
• W2931366185 hasConcept C151956035 @default.
• W2931366185 hasConcept C156957248 @default.
• W2931366185 hasConcept C17923572 @default.
• W2931366185 hasConcept C2777297899 @default.
• W2931366185 hasConcept C2778292576 @default.
• W2931366185 hasConcept C2779742542 @default.
• W2931366185 hasConcept C50382708 @default.
• W2931366185 hasConcept C509974204 @default.
• W2931366185 hasConcept C530470458 @default.
• W2931366185 hasConcept C71924100 @default.
• W2931366185 hasConcept C90924648 @default.
• W2931366185 hasConceptScore W2931366185C121608353 @default.
• W2931366185 hasConceptScore W2931366185C126322002 @default.
• W2931366185 hasConceptScore W2931366185C143998085 @default.
• W2931366185 hasConceptScore W2931366185C151956035 @default.
• W2931366185 hasConceptScore W2931366185C156957248 @default.
• W2931366185 hasConceptScore W2931366185C17923572 @default.
• W2931366185 hasConceptScore W2931366185C2777297899 @default.
• W2931366185 hasConceptScore W2931366185C2778292576 @default.
• W2931366185 hasConceptScore W2931366185C2779742542 @default.
• W2931366185 hasConceptScore W2931366185C50382708 @default.
• W2931366185 hasConceptScore W2931366185C509974204 @default.
• W2931366185 hasConceptScore W2931366185C530470458 @default.
• W2931366185 hasConceptScore W2931366185C71924100 @default.
• W2931366185 hasConceptScore W2931366185C90924648 @default.
• W2931366185 hasIssue "4" @default.
• W2931366185 hasLocation W29313661851 @default.
• W2931366185 hasLocation W29313661852 @default.
• W2931366185 hasLocation W29313661853 @default.
• W2931366185 hasLocation W29313661854 @default.
• W2931366185 hasOpenAccess W2931366185 @default.
• W2931366185 hasPrimaryLocation W29313661851 @default.
• W2931366185 hasRelatedWork W2011561999 @default.

• next