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- W29320504 abstract "ABSTRACT The data in this report shows that helper activity not only augments but is required for the generation of murine cytotoxic T cells. Since this helper activity is required in vivo , it may play a physiologic role in the activation of cytotoxic T lymphocyte precursors (CTL.P). Furthermore, the data demonstrate that unprimed CTL.P in vivo have different helper requirements than antigen primed CTL.P in vitro. In conjunction with data from other laboratories, our findings indicate that the helper activity required for CTL.P is not solely the T cell growth factor, interleukin 2. Our evidence favors a requirement for a second T cell signal, most probably for differentiation." @default.
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- W29320504 date "1982-01-01" @default.
- W29320504 modified "2023-09-26" @default.
- W29320504 title "ANALYSIS OF HELPER REQUIREMENTS FOR THE DIFFERENTIATION OF CYTOTOXIC T CELL PRECURSORS" @default.
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- W29320504 doi "https://doi.org/10.1016/b978-0-12-722380-3.50022-2" @default.
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