Matches in SemOpenAlex for { <https://semopenalex.org/work/W2932083559> ?p ?o ?g. }
- W2932083559 endingPage "7856" @default.
- W2932083559 startingPage "7847" @default.
- W2932083559 abstract "Significance Elucidation of neuropeptide–receptor pairs is essential for the investigation of peptidergic signalling processes. Although sequence alignment and molecular phylogenetic analysis can easily predict G protein-coupled receptors for homologous neuropeptides, these methods cannot predict receptors for novel peptides, so many neuropeptide–receptor pairs remain to be identified. We used our original machine-learning system, peptide descriptor-incorporated support vector machine, to predict multiple neuropeptide–receptor pairs of the vertebrate sister group, Ciona robusta . The Ciona -specific neuropeptide–receptor pairs were validated with cell-based pharmacological assays, showing biological roles for the neuropeptides in a model protochordate. Because of the critical phylogenetic position of Ciona , the present study also elucidates the evolutionary processes underlying neuropeptidergic systems in chordates." @default.
- W2932083559 created "2019-04-11" @default.
- W2932083559 creator A5014132611 @default.
- W2932083559 creator A5016118872 @default.
- W2932083559 creator A5026120081 @default.
- W2932083559 creator A5040002011 @default.
- W2932083559 creator A5046211758 @default.
- W2932083559 creator A5062032512 @default.
- W2932083559 creator A5080937607 @default.
- W2932083559 date "2019-04-01" @default.
- W2932083559 modified "2023-10-10" @default.
- W2932083559 title "Repertoires of G protein-coupled receptors for <i>Ciona</i> -specific neuropeptides" @default.
- W2932083559 cites W1596429464 @default.
- W2932083559 cites W1664750859 @default.
- W2932083559 cites W1797708726 @default.
- W2932083559 cites W1972100873 @default.
- W2932083559 cites W1977429173 @default.
- W2932083559 cites W1980667095 @default.
- W2932083559 cites W1987520856 @default.
- W2932083559 cites W1988037271 @default.
- W2932083559 cites W1995503870 @default.
- W2932083559 cites W2001936817 @default.
- W2932083559 cites W2009371644 @default.
- W2932083559 cites W2014847983 @default.
- W2932083559 cites W2015865718 @default.
- W2932083559 cites W2017891440 @default.
- W2932083559 cites W2018991353 @default.
- W2932083559 cites W2020125455 @default.
- W2932083559 cites W2023058125 @default.
- W2932083559 cites W2023628415 @default.
- W2932083559 cites W2026551295 @default.
- W2932083559 cites W2028274002 @default.
- W2932083559 cites W2028423171 @default.
- W2932083559 cites W2029708244 @default.
- W2932083559 cites W2032980299 @default.
- W2932083559 cites W2039610940 @default.
- W2932083559 cites W2046183549 @default.
- W2932083559 cites W2051561558 @default.
- W2932083559 cites W2060851522 @default.
- W2932083559 cites W2070405413 @default.
- W2932083559 cites W2072801720 @default.
- W2932083559 cites W2100672820 @default.
- W2932083559 cites W2100729071 @default.
- W2932083559 cites W2102502076 @default.
- W2932083559 cites W2106401878 @default.
- W2932083559 cites W2107063279 @default.
- W2932083559 cites W2115888213 @default.
- W2932083559 cites W2119153171 @default.
- W2932083559 cites W2124790653 @default.
- W2932083559 cites W2125957493 @default.
- W2932083559 cites W2129202098 @default.
- W2932083559 cites W2141052558 @default.
- W2932083559 cites W2144775551 @default.
- W2932083559 cites W2148972970 @default.
- W2932083559 cites W2152800101 @default.
- W2932083559 cites W2153225946 @default.
- W2932083559 cites W2154594984 @default.
- W2932083559 cites W2155070406 @default.
- W2932083559 cites W2159718916 @default.
- W2932083559 cites W2166410137 @default.
- W2932083559 cites W2170960297 @default.
- W2932083559 cites W2194756172 @default.
- W2932083559 cites W2213443318 @default.
- W2932083559 cites W2215520647 @default.
- W2932083559 cites W2311203695 @default.
- W2932083559 cites W2513544049 @default.
- W2932083559 cites W2739999456 @default.
- W2932083559 cites W2787904428 @default.
- W2932083559 cites W2791639407 @default.
- W2932083559 cites W2791708148 @default.
- W2932083559 cites W2903037276 @default.
- W2932083559 cites W4243516034 @default.
- W2932083559 cites W851765943 @default.
- W2932083559 doi "https://doi.org/10.1073/pnas.1816640116" @default.
- W2932083559 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6475428" @default.
- W2932083559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30936317" @default.
- W2932083559 hasPublicationYear "2019" @default.
- W2932083559 type Work @default.
- W2932083559 sameAs 2932083559 @default.
- W2932083559 citedByCount "32" @default.
- W2932083559 countsByYear W29320835592019 @default.
- W2932083559 countsByYear W29320835592020 @default.
- W2932083559 countsByYear W29320835592021 @default.
- W2932083559 countsByYear W29320835592022 @default.
- W2932083559 countsByYear W29320835592023 @default.
- W2932083559 crossrefType "journal-article" @default.
- W2932083559 hasAuthorship W2932083559A5014132611 @default.
- W2932083559 hasAuthorship W2932083559A5016118872 @default.
- W2932083559 hasAuthorship W2932083559A5026120081 @default.
- W2932083559 hasAuthorship W2932083559A5040002011 @default.
- W2932083559 hasAuthorship W2932083559A5046211758 @default.
- W2932083559 hasAuthorship W2932083559A5062032512 @default.
- W2932083559 hasAuthorship W2932083559A5080937607 @default.
- W2932083559 hasBestOaLocation W29320835591 @default.
- W2932083559 hasConcept C104317684 @default.
- W2932083559 hasConcept C118303440 @default.
- W2932083559 hasConcept C135285700 @default.
- W2932083559 hasConcept C170493617 @default.