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- W293256543 abstract "The microsomal monooxygenase system does produce reactive radicals that might cause cytotoxic effects. These radicals can originate from the oxidase activity, peroxygenase activity, reductase activity or hydroxylase activity of the components, mainly those of cytochrome P450. It appears that the isoform of cytochrome P450 which does produce radicals to the highest extent is ethanol-inducible cytochrome P450 2E1 (CYP2E1). This overview summarizes the results dealing with the importance of P450 for radical production and in particular that of CYP2E1." @default.
- W293256543 created "2016-06-24" @default.
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- W293256543 date "1993-01-01" @default.
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- W293256543 title "Ethanol-Inducible Cytochrome P450 2E1. Regulation, Radical Formation and Toxicological Importance." @default.
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- W293256543 doi "https://doi.org/10.1007/978-3-0348-9116-5_25" @default.
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