Matches in SemOpenAlex for { <https://semopenalex.org/work/W2932666194> ?p ?o ?g. }
- W2932666194 endingPage "175883591983896" @default.
- W2932666194 startingPage "175883591983896" @default.
- W2932666194 abstract "Currently, preoperative chemoradiotherapy, perioperative chemotherapy and preoperative chemotherapy are recommended by NCCN, ESMO and Japanese guidelines respectively for resectable esophageal and junctional cancer. However, these recommendations are mainly based on esophageal cancer research. Therefore, specific for esophagogastric junction cancer, we conducted the first systematic review and network meta-analysis to rank all potential treatments simultaneously and hierarchically.Record retrieval was conducted in PubMed, Web of Science, Cochrane Central Register of Controlled Trials, Embase, ASCO and ESMO Meeting Library from inception to September 2018. Regarding time-to-event survival data, randomized controlled trials featuring comparisons between different multimodal treatments against resectable esophagogastric junction cancer were eligible. Overall survival was the endpoint. Network calculation was based on a random-effects model and the relative ranking of each node was numerically indicated by P-score (CRD42018110369, registration identifier of the meta-analysis in PROSPERO.).Eight studies were included in our systematic review, corresponding to 1218 patients. Regarding overall survival, 'PreCRT' (preoperative chemoradiotherapy) topped the hierarchy (HR 1.00, P-score = 0.823), better than 'PeriCT' (perioperative chemotherapy; HR 1.32, P-score = 0.591) and 'PreCT' (preoperative chemotherapy; HR 1.54, P-score = 0.428). In sensitivity analyses, irrespective of interchanging to fixed-effects model or removing potentially heterogeneous studies, relative rankings remained stable and 'PreCRT' was still the optimal node.Preoperative chemoradiotherapy could potentially be the optimal multimodal treatment, which displayed more overall survival benefits than perioperative chemotherapy and preoperative chemotherapy among resectable esophagogastric junction cancer patients. To further verify our pooled results, more randomized trials will be needed to compare preoperative chemoradiotherapy with perioperative chemotherapy (especially FLOT-based regimens)." @default.
- W2932666194 created "2019-04-11" @default.
- W2932666194 creator A5039207540 @default.
- W2932666194 creator A5054898933 @default.
- W2932666194 creator A5059393102 @default.
- W2932666194 creator A5067612393 @default.
- W2932666194 creator A5079375938 @default.
- W2932666194 creator A5084930619 @default.
- W2932666194 date "2019-01-01" @default.
- W2932666194 modified "2023-10-16" @default.
- W2932666194 title "Multimodal treatments for resectable esophagogastric junction cancer: a systematic review and network meta-analysis" @default.
- W2932666194 cites W2033008994 @default.
- W2932666194 cites W2074134583 @default.
- W2932666194 cites W2089574951 @default.
- W2932666194 cites W2098923148 @default.
- W2932666194 cites W2099918668 @default.
- W2932666194 cites W2109051507 @default.
- W2932666194 cites W2114489245 @default.
- W2932666194 cites W2115072149 @default.
- W2932666194 cites W2122352172 @default.
- W2932666194 cites W2123784961 @default.
- W2932666194 cites W2144625636 @default.
- W2932666194 cites W2146834306 @default.
- W2932666194 cites W2162304120 @default.
- W2932666194 cites W2162405246 @default.
- W2932666194 cites W2165299947 @default.
- W2932666194 cites W2165982376 @default.
- W2932666194 cites W2537321298 @default.
- W2932666194 cites W2585375914 @default.
- W2932666194 cites W2588681363 @default.
- W2932666194 cites W2729056212 @default.
- W2932666194 cites W2733330634 @default.
- W2932666194 cites W2763640718 @default.
- W2932666194 cites W2766346103 @default.
- W2932666194 cites W2781525129 @default.
- W2932666194 cites W2797145364 @default.
- W2932666194 cites W2888636474 @default.
- W2932666194 cites W2889646458 @default.
- W2932666194 cites W4211007657 @default.
- W2932666194 doi "https://doi.org/10.1177/1758835919838963" @default.
- W2932666194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6446435" @default.
- W2932666194 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31044021" @default.
- W2932666194 hasPublicationYear "2019" @default.
- W2932666194 type Work @default.
- W2932666194 sameAs 2932666194 @default.
- W2932666194 citedByCount "4" @default.
- W2932666194 countsByYear W29326661942020 @default.
- W2932666194 countsByYear W29326661942021 @default.
- W2932666194 countsByYear W29326661942022 @default.
- W2932666194 countsByYear W29326661942023 @default.
- W2932666194 crossrefType "journal-article" @default.
- W2932666194 hasAuthorship W2932666194A5039207540 @default.
- W2932666194 hasAuthorship W2932666194A5054898933 @default.
- W2932666194 hasAuthorship W2932666194A5059393102 @default.
- W2932666194 hasAuthorship W2932666194A5067612393 @default.
- W2932666194 hasAuthorship W2932666194A5079375938 @default.
- W2932666194 hasAuthorship W2932666194A5084930619 @default.
- W2932666194 hasBestOaLocation W29326661941 @default.
- W2932666194 hasConcept C121608353 @default.
- W2932666194 hasConcept C126322002 @default.
- W2932666194 hasConcept C141071460 @default.
- W2932666194 hasConcept C143998085 @default.
- W2932666194 hasConcept C168563851 @default.
- W2932666194 hasConcept C187960798 @default.
- W2932666194 hasConcept C2776478404 @default.
- W2932666194 hasConcept C2778424827 @default.
- W2932666194 hasConcept C2779742542 @default.
- W2932666194 hasConcept C2780962732 @default.
- W2932666194 hasConcept C31174226 @default.
- W2932666194 hasConcept C526805850 @default.
- W2932666194 hasConcept C71924100 @default.
- W2932666194 hasConcept C95190672 @default.
- W2932666194 hasConceptScore W2932666194C121608353 @default.
- W2932666194 hasConceptScore W2932666194C126322002 @default.
- W2932666194 hasConceptScore W2932666194C141071460 @default.
- W2932666194 hasConceptScore W2932666194C143998085 @default.
- W2932666194 hasConceptScore W2932666194C168563851 @default.
- W2932666194 hasConceptScore W2932666194C187960798 @default.
- W2932666194 hasConceptScore W2932666194C2776478404 @default.
- W2932666194 hasConceptScore W2932666194C2778424827 @default.
- W2932666194 hasConceptScore W2932666194C2779742542 @default.
- W2932666194 hasConceptScore W2932666194C2780962732 @default.
- W2932666194 hasConceptScore W2932666194C31174226 @default.
- W2932666194 hasConceptScore W2932666194C526805850 @default.
- W2932666194 hasConceptScore W2932666194C71924100 @default.
- W2932666194 hasConceptScore W2932666194C95190672 @default.
- W2932666194 hasLocation W29326661941 @default.
- W2932666194 hasLocation W29326661942 @default.
- W2932666194 hasLocation W29326661943 @default.
- W2932666194 hasLocation W29326661944 @default.
- W2932666194 hasOpenAccess W2932666194 @default.
- W2932666194 hasPrimaryLocation W29326661941 @default.
- W2932666194 hasRelatedWork W1997407706 @default.
- W2932666194 hasRelatedWork W2392949029 @default.
- W2932666194 hasRelatedWork W2914141471 @default.
- W2932666194 hasRelatedWork W2996633490 @default.
- W2932666194 hasRelatedWork W3096683796 @default.
- W2932666194 hasRelatedWork W3119103806 @default.