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- W2933412100 abstract "Four new sesquiterpenoids，including three nor-cinalbicane type sesquiterpenoids, named Jasminol A, G, H (1–3) and one eremophilene-type sesquiterpenoid, named Jasminol B (4) together with nine known compounds (5–13) were isolated from the stems of Jasminum officinale L. The structures of new compound were elucidated on the base of IR, HR-ESI-MS, 1D NMR, 2D NMR and DEPT analysis, and the absolute configurations were determined by single-crystal X-ray diffraction analysis. In addition, the anti-inflammatory activity of isolated compounds was evaluated using lipopolysaccharide (LPS)-induced murine macrophage RAW264.7, and compounds 1–4 exhibited a moderate inhibition of LPS-induced nitric oxide (NO) production in RAW264.7 cells with IC50 values of 20.56 ± 1.31, 30.12 ± 0.89, 30.35 ± 2.72 and 31.60 ± 1.69 μM, respectively, and CC50 values >200 uM." @default.
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- W2933412100 date "2019-06-01" @default.
- W2933412100 modified "2023-10-11" @default.
- W2933412100 title "Four new sesquiterpenoids with anti-inflammatory activity from the stems of Jasminum officinale" @default.
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- W2933412100 doi "https://doi.org/10.1016/j.fitote.2019.03.029" @default.
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