Matches in SemOpenAlex for { <https://semopenalex.org/work/W2933414168> ?p ?o ?g. }
- W2933414168 endingPage "474" @default.
- W2933414168 startingPage "467" @default.
- W2933414168 abstract "Abstract Objective: The objective of this study was to assess differences in myocardial systolic and diastolic function and vascular function in children 2−5 years of age born to diabetic as compared to non-diabetic mothers. Methods: This study was a retrospective cohort conducted in 2016 at The Aga Khan University Hospital, Karachi, Pakistan. It included children between 2 and 5 years of age born to mothers with and without exposure to diabetes in utero (n = 68 in each group) and who were appropriate for gestational age. Myocardial morphology and function using echocardiogram and carotid intima media thickness (cIMT) and pulse wave velocity was performed to evaluate cardiac function as well as macrovascular remodelling in these children. Multiple linear regression was used to compare the groups. Results: There was no significant difference in cardiac morphology, myocardial systolic and diastolic function, and macrovascular assessment between the exposed and unexposed groups of AGA children. Subgroup analysis demonstrated a significantly decreased mitral E/A ratio in children whose mothers were on medications as compared to those on dietary control (median [IQR] = 1.7 [1.6–1.9] and 1.56 [1.4–1.7], respectively, p = 0.02), and a higher cIMT in children whose mothers were on medication as compared to controls (0.48 [0.44–0.52] and 0.46 [0.44–0.50], respectively, p = 0.03). Conclusion: In utero exposure to uncontrolled maternal diabetes has an effect on the cardiovascular structure and function in children aged 2−5 years. However, future work requires long-term follow-up from fetal to adult life to assess these changes over the life course." @default.
- W2933414168 created "2019-04-11" @default.
- W2933414168 creator A5000066671 @default.
- W2933414168 creator A5018609633 @default.
- W2933414168 creator A5021833342 @default.
- W2933414168 creator A5039784962 @default.
- W2933414168 creator A5043878348 @default.
- W2933414168 creator A5055029139 @default.
- W2933414168 creator A5059966414 @default.
- W2933414168 creator A5070422016 @default.
- W2933414168 creator A5089423032 @default.
- W2933414168 date "2019-04-01" @default.
- W2933414168 modified "2023-09-27" @default.
- W2933414168 title "Is the child at risk? Cardiovascular remodelling in children born to diabetic mothers" @default.
- W2933414168 cites W1941012826 @default.
- W2933414168 cites W1965981551 @default.
- W2933414168 cites W1975162123 @default.
- W2933414168 cites W1983008967 @default.
- W2933414168 cites W1986160011 @default.
- W2933414168 cites W2000165139 @default.
- W2933414168 cites W2020267609 @default.
- W2933414168 cites W2035438996 @default.
- W2933414168 cites W2044247442 @default.
- W2933414168 cites W2046423215 @default.
- W2933414168 cites W2063998910 @default.
- W2933414168 cites W2069636519 @default.
- W2933414168 cites W2069782756 @default.
- W2933414168 cites W2070438820 @default.
- W2933414168 cites W2075213782 @default.
- W2933414168 cites W2075887972 @default.
- W2933414168 cites W2092652418 @default.
- W2933414168 cites W2093195932 @default.
- W2933414168 cites W2094912906 @default.
- W2933414168 cites W2095374297 @default.
- W2933414168 cites W2103974198 @default.
- W2933414168 cites W2107634322 @default.
- W2933414168 cites W2109078923 @default.
- W2933414168 cites W2123780246 @default.
- W2933414168 cites W2131998216 @default.
- W2933414168 cites W2133295330 @default.
- W2933414168 cites W2154612721 @default.
- W2933414168 cites W2160827694 @default.
- W2933414168 cites W2165516918 @default.
- W2933414168 cites W2175243786 @default.
- W2933414168 cites W2213078298 @default.
- W2933414168 cites W2322613273 @default.
- W2933414168 cites W2588111394 @default.
- W2933414168 cites W2775702235 @default.
- W2933414168 doi "https://doi.org/10.1017/s1047951119000040" @default.
- W2933414168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30940265" @default.
- W2933414168 hasPublicationYear "2019" @default.
- W2933414168 type Work @default.
- W2933414168 sameAs 2933414168 @default.
- W2933414168 citedByCount "8" @default.
- W2933414168 countsByYear W29334141682020 @default.
- W2933414168 countsByYear W29334141682021 @default.
- W2933414168 countsByYear W29334141682022 @default.
- W2933414168 countsByYear W29334141682023 @default.
- W2933414168 crossrefType "journal-article" @default.
- W2933414168 hasAuthorship W2933414168A5000066671 @default.
- W2933414168 hasAuthorship W2933414168A5018609633 @default.
- W2933414168 hasAuthorship W2933414168A5021833342 @default.
- W2933414168 hasAuthorship W2933414168A5039784962 @default.
- W2933414168 hasAuthorship W2933414168A5043878348 @default.
- W2933414168 hasAuthorship W2933414168A5055029139 @default.
- W2933414168 hasAuthorship W2933414168A5059966414 @default.
- W2933414168 hasAuthorship W2933414168A5070422016 @default.
- W2933414168 hasAuthorship W2933414168A5089423032 @default.
- W2933414168 hasConcept C111566952 @default.
- W2933414168 hasConcept C126322002 @default.
- W2933414168 hasConcept C131872663 @default.
- W2933414168 hasConcept C134018914 @default.
- W2933414168 hasConcept C164705383 @default.
- W2933414168 hasConcept C172680121 @default.
- W2933414168 hasConcept C187212893 @default.
- W2933414168 hasConcept C201614185 @default.
- W2933414168 hasConcept C2778198053 @default.
- W2933414168 hasConcept C2778319312 @default.
- W2933414168 hasConcept C2778376644 @default.
- W2933414168 hasConcept C2779234561 @default.
- W2933414168 hasConcept C2779339615 @default.
- W2933414168 hasConcept C2779434492 @default.
- W2933414168 hasConcept C2987047532 @default.
- W2933414168 hasConcept C46973012 @default.
- W2933414168 hasConcept C54355233 @default.
- W2933414168 hasConcept C555293320 @default.
- W2933414168 hasConcept C57900726 @default.
- W2933414168 hasConcept C71924100 @default.
- W2933414168 hasConcept C72563966 @default.
- W2933414168 hasConcept C84393581 @default.
- W2933414168 hasConcept C86803240 @default.
- W2933414168 hasConceptScore W2933414168C111566952 @default.
- W2933414168 hasConceptScore W2933414168C126322002 @default.
- W2933414168 hasConceptScore W2933414168C131872663 @default.
- W2933414168 hasConceptScore W2933414168C134018914 @default.
- W2933414168 hasConceptScore W2933414168C164705383 @default.
- W2933414168 hasConceptScore W2933414168C172680121 @default.
- W2933414168 hasConceptScore W2933414168C187212893 @default.